Literature DB >> 1276998

Two toxic indole alkaloids from Penicillium islandicum.

R J Cole, J W Kirksey, H G Cutler, D M Wilson, G Morgan-Jones.   

Abstract

Two new isomeric metabolites, toxins A and B, were isolated from culture extracts of Penicillium islandicum. Both toxins had a molecular formula of C16H15O2N2Cl, and physical and chemical analyses indicated that they were indole alkaloids. LD50 of toxin A was about 75-125 mg/kg in day-old cockerels. Insufficient toxin B was available to determine accurate LD50 values. Toxin A moderately inhibited growth of wheat coleoptiles but did not inhibit growth of week-old intact corn and bean plants. Toxin B showed no plant-growth inhibition.

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Year:  1976        PMID: 1276998     DOI: 10.1139/m76-107

Source DB:  PubMed          Journal:  Can J Microbiol        ISSN: 0008-4166            Impact factor:   2.419


  5 in total

1.  Penicillium rubrum and Penicillium biforme, new sources of rugulovasines A and B.

Authors:  J W Dorner; R J Cole; R Hill; D Wicklow; R H Cox
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2.  A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin, toxins from Penicillium islandicum Sopp.

Authors:  A C Ghosh; A Manmade; A Bousquet; J M Townsend; A L Demain
Journal:  Experientia       Date:  1978-06-15

Review 3.  Total synthesis, biosynthesis and biological profiles of clavine alkaloids.

Authors:  Stephanie R McCabe; Peter Wipf
Journal:  Org Biomol Chem       Date:  2016-05-24       Impact factor: 3.876

Review 4.  Ergot alkaloids--sources, structures and analytical methods.

Authors:  M Flieger; M Wurst; R Shelby
Journal:  Folia Microbiol (Praha)       Date:  1997       Impact factor: 2.629

5.  Delimitation and characterisation of Talaromyces purpurogenus and related species.

Authors:  N Yilmaz; J Houbraken; E S Hoekstra; J C Frisvad; C M Visagie; R A Samson
Journal:  Persoonia       Date:  2012-11-12       Impact factor: 11.051

  5 in total

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