Literature DB >> 12769010

Solitary enchondromas: is radiographic follow-up sufficient in patients with asymptomatic lesions?

P E Müller1, H R Dürr, B Wegener, C Pellengahr, M Maier, V Jansson.   

Abstract

Enchondromas are benign cartilaginous tumours and rarely transform into chondrosarcomas. Curettage is usually performed, and a low rate of complications is assumed. We analysed retrospectively data from 73 patients with enchondromas treated by curettage with respect to symptoms, therapy, complications and recurrences. All patients were treated by curettage of the tumour, in most cases followed by cancellous bone grafting. Twenty-three percent of the patients presented a complication. There were two recurrences but no malignant transformations in the follow-up period. During the same time period 29 patients with chondrosarcomas were treated, including two secondary chondrosarcomas. One had a recurrence of a benign enchondroma of the metacarpal and developed a pulmonary metastasis from a chondrosarcoma. The other was a patient with Ollier's disease who had a secondary chondrosarcoma of the radius. Malignant transformation of a solitary enchondroma to a chondrosarcoma is rare. On the other hand the complication rate of enchondroma curettage is considerable. Regular radiological follow-up of asymptomatic enchondromas may therefore be the better option.

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Mesh:

Year:  2003        PMID: 12769010

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  6 in total

1.  Predicting Fracture Risk for Enchondroma of the Hand.

Authors:  Scott Riester; Rishi Ramaesch; Doris Wenger; Andre van Wijnen; Sanjeev Kakar
Journal:  Hand (N Y)       Date:  2016-02-02

2.  [Comment on the work "Therapy of enchondroma in long bones" (H. Steckel, M. Oldenburg, R.T. Müller)].

Authors:  W Mutschler; W Sienel
Journal:  Unfallchirurg       Date:  2005-06       Impact factor: 1.000

3.  No recurrences in selected patients after curettage with cryotherapy for grade I chondrosarcomas.

Authors:  Badio S Souna; Nicolas Belot; Hélène Duval; Frantz Langlais; Hervé Thomazeau
Journal:  Clin Orthop Relat Res       Date:  2010-01-07       Impact factor: 4.176

4.  Pathologic Fractures in Benign Neoplasms of the Fingers.

Authors:  Kamilcan Oflazoglu; Jonathan Lans; René M Castelein; Santiago A Lozano Calderón; Neal C Chen
Journal:  Hand (N Y)       Date:  2019-06-17

5.  TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells.

Authors:  Naohiro Shinohara; Shingo Maeda; Yuhei Yahiro; Daisuke Sakuma; Kanehiro Matsuyama; Katsuyuki Imamura; Ichiro Kawamura; Takao Setoguchi; Yasuhiro Ishidou; Satoshi Nagano; Setsuro Komiya
Journal:  Sci Rep       Date:  2017-10-18       Impact factor: 4.379

6.  Radiologic follow-up of untreated enchondroma and atypical cartilaginous tumors in the long bones.

Authors:  Claudia Deckers; Bart H W Schreuder; Gerjon Hannink; Jacky W J de Rooy; Ingrid C M van der Geest
Journal:  J Surg Oncol       Date:  2016-10-03       Impact factor: 3.454

  6 in total

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