B Zhou1, S Lü, X Chen. 1. Department of Otorhinolaryngology, Affiliated Hospital of Guangdong Medical College, Guangdong, Zhanjang 524001, China. cj3a@163.net
Abstract
OBJECTIVE: To investigate the immune function of erythrocyte (RBC) and leucocyte (WBC), and variety of the interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) among patients with allergic rhinitis. METHODS: IL-4 and IFN-gamma secreted by peripheral blood mononuclear cells (PBMC) were measured and compared with immune adhesive and BA-ELISA method. RESULTS: Results showed the RBC and WBC immune adhesive function and IFN-gamma were significantly decreased than of the control, and IL-4 activity were significantly higher than the controls (P < 0.01) in patients with perennial allergic rhinitis. CONCLUSION: These results suggest that RBC and WBC the immune function and IL-4 and IFN-gamma may play an important role in allergic rhinitis.
OBJECTIVE: To investigate the immune function of erythrocyte (RBC) and leucocyte (WBC), and variety of the interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) among patients with allergic rhinitis. METHODS:IL-4 and IFN-gamma secreted by peripheral blood mononuclear cells (PBMC) were measured and compared with immune adhesive and BA-ELISA method. RESULTS: Results showed the RBC and WBC immune adhesive function and IFN-gamma were significantly decreased than of the control, and IL-4 activity were significantly higher than the controls (P < 0.01) in patients with perennial allergic rhinitis. CONCLUSION: These results suggest that RBC and WBC the immune function and IL-4 and IFN-gamma may play an important role in allergic rhinitis.