| Literature DB >> 12768035 |
Virginie Prod'homme1, Christelle Retière, Ralitza Valtcheva, Marc Bonneville, Marie-Martine Hallet.
Abstract
The impact of natural polymorphism in a cytomegalovirus-dominant HLA-B(*)1801-restricted epitope, IE1(199-206), on the specific responses of T-cell clones was assessed by measuring their cytolytic activity against target cells expressing mutated recombinant IE1 proteins. Our results suggest an in vivo selection of T lymphocytes that cross-react with multiple IE1 variants.Entities:
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Year: 2003 PMID: 12768035 PMCID: PMC156178 DOI: 10.1128/jvi.77.12.7139-7142.2003
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103