Literature DB >> 12767951

Renin-angiotensin system and atherothrombotic disease: from genes to treatment.

Douglas S Jacoby1, Daniel J Rader.   

Abstract

The renin-angiotensin system plays a central role in the pathogenesis of cardiovascular disease. At the molecular and cellular levels, angiotensin II, the main effector peptide of the system, stimulates key components of atherosclerosis. Trials in animals and humans indicate that blocking renin-angiotensin system pathways decreases atherosclerotic plaque progression and ischemic events. This review provides a broad overview of the entire role of the renin-angiotensin system in atherothrombotic disease, ranging from molecular pathways to human genetics to the latest clinical trials.

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Year:  2003        PMID： 12767951     DOI： 10.1001/archinte.163.10.1155

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN： 0003-9926


  25 in total

Review 1.  Inflammation and atherosclerosis.

Authors:  Mehdi H Shishehbor; Deepak L Bhatt
Journal:  Curr Atheroscler Rep       Date:  2004-03       Impact factor: 5.113

Review 2.  Atherosclerotic renal artery stenosis, ACE inhibitors, and avoiding cardiovascular death.

Authors:  John Main
Journal:  Heart       Date:  2005-04       Impact factor: 5.994

Review 3.  Endothelial progenitor cells in cardiovascular diseases.

Authors:  Poay Sian Sabrina Lee; Kian Keong Poh
Journal:  World J Stem Cells       Date:  2014-07-26       Impact factor: 5.326

4.  Agonistic antibody to angiotensin II type 1 receptor accelerates atherosclerosis in ApoE-/- mice.

Authors:  Weijuan Li; Yaoqi Chen; Songhai Li; Xiaopeng Guo; Wenping Zhou; Qiutang Zeng; Yuhua Liao; Yumiao Wei
Journal:  Am J Transl Res       Date:  2014-11-22       Impact factor: 4.060

5.  Effects of ACE inhibition on circulating endothelial progenitor cells, vascular damage, and oxidative stress in hypertensive patients.

Authors:  Francesco Cacciatore; Giuseppe Bruzzese; Dino Franco Vitale; Antonio Liguori; Filomena de Nigris; Carmela Fiorito; Teresa Infante; Francesco Donatelli; Pellegrino Biagio Minucci; Louis Joseph Ignarro; Claudio Napoli
Journal:  Eur J Clin Pharmacol       Date:  2011-03-29       Impact factor: 2.953

Review 6.  Pharmacological strategies to reduce cardiovascular risk in type 2 diabetes mellitus: an update.

Authors:  Marcel M C Hovens; Jouke T Tamsma; Edith D Beishuizen; Menno V Huisman
Journal:  Drugs       Date:  2005       Impact factor: 9.546

Review 7.  Extra-skeletal effects of vitamin D deficiency in chronic kidney disease.

Authors:  Michel Chonchol; Jessica Kendrick; Giovanni Targher
Journal:  Ann Med       Date:  2011-01-10       Impact factor: 4.709

8.  Replacement of dietary soy protein isolate with concentrates of soy 7S or 11S globulin has minimal or no effects on plasma lipoprotein profiles and biomarkers of coronary risk in monkeys.

Authors:  Michael R Adams; Mary S Anthony; Haiying Chen; Thomas B Clarkson
Journal:  Atherosclerosis       Date:  2007-03-09       Impact factor: 5.162

9.  Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins.

Authors:  Annemarie E Silver; Demetra D Christou; Anthony J Donato; Stacy D Beske; Kerrie L Moreau; Katherine A Magerko; Douglas R Seals
Journal:  J Vasc Res       Date:  2009-08-06       Impact factor: 1.934

Review 10.  The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies.

Authors:  Fabrizio Montecucco; Aldo Pende; François Mach
Journal:  Mediators Inflamm       Date:  2009-04-14       Impact factor: 4.711
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