Literature DB >> 12767851

Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1).

W N Fawley1, J Freeman, M H Wilcox.   

Abstract

We used three different DNA fingerprinting techniques and clindamycin susceptibility testing to confirm that Clostridium difficile PCR ribotype I isolates can be divided into two subclones. This observation may permit a better understanding of the epidemiology and pathogenicity of C. difficile infection.

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Year:  2003        PMID: 12767851     DOI: 10.1016/s0195-6701(03)00079-3

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  7 in total

1.  Comparative analysis of prevalence, risk factors, and molecular epidemiology of antibiotic-associated diarrhea due to Clostridium difficile, Clostridium perfringens, and Staphylococcus aureus.

Authors:  N J Asha; D Tompkins; M H Wilcox
Journal:  J Clin Microbiol       Date:  2006-08       Impact factor: 5.948

2.  Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains.

Authors:  R A Stabler; D N Gerding; J G Songer; D Drudy; J S Brazier; H T Trinh; A A Witney; J Hinds; B W Wren
Journal:  J Bacteriol       Date:  2006-10       Impact factor: 3.490

3.  Increased rate of DNA recovery from United Kingdom epidemic Clostridium difficile PCR ribotype 1 strains stored cryogenically.

Authors:  N J Asha; W N Fawley; J Freeman; M H Wilcox
Journal:  J Clin Microbiol       Date:  2005-11       Impact factor: 5.948

4.  Molecular epidemiology of endemic Clostridium difficile infection and the significance of subtypes of the United Kingdom epidemic strain (PCR ribotype 1).

Authors:  Warren N Fawley; Peter Parnell; Paul Verity; Jane Freeman; Mark H Wilcox
Journal:  J Clin Microbiol       Date:  2005-06       Impact factor: 5.948

5.  Correlation of disease severity with fecal toxin levels in patients with Clostridium difficile-associated diarrhea and distribution of PCR ribotypes and toxin yields in vitro of corresponding isolates.

Authors:  Thomas Akerlund; Bo Svenungsson; Asa Lagergren; Lars G Burman
Journal:  J Clin Microbiol       Date:  2006-02       Impact factor: 5.948

6.  Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species.

Authors:  Kevin Keel; Jon S Brazier; Karen W Post; Scott Weese; J Glenn Songer
Journal:  J Clin Microbiol       Date:  2007-04-11       Impact factor: 5.948

7.  Aerial dissemination of Clostridium difficile spores.

Authors:  Katherine Roberts; Caroline F Smith; Anna M Snelling; Kevin G Kerr; Kathleen R Banfield; P Andrew Sleigh; Clive B Beggs
Journal:  BMC Infect Dis       Date:  2008-01-24       Impact factor: 3.090

  7 in total

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