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Literature DB >> 12766015

CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism.

Andrea Gaedigk¹, Darren L Ryder, L DiAnne Bradford, J Steven Leeder.

Abstract

Entities: Gene

Mesh：

Substances：
Cytochrome P-450 CYP2D6

Year: 2003 PMID： 12766015 DOI： 10.1373/49.6.1008

Source DB: PubMed Journal: Clin Chem ISSN： 0009-9147 Impact factor: 8.327

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Cited

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17 in total

1. BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors.

Authors: Caterina Chianella; Daniela Gragnaniello; Pierpaolo Maisano Delser; Maria Francesca Visentini; Elisabetta Sette; Maria Rosaria Tola; Guido Barbujani; Silvia Fuselli
Journal: Eur J Clin Pharmacol Date: 2011-06-01 Impact factor: 2.953

2. Identification of CYP2D6 impaired functional alleles in Mexican Americans.

Authors: Huai-Rong Luo; Andrea Gaedigk; Vasileios Aloumanis; Yu-Jui Yvonne Wan
Journal: Eur J Clin Pharmacol Date: 2005-11-08 Impact factor: 2.953

Review 3. Cancer treatment and pharmacogenetics of cytochrome P450 enzymes.

Authors: Ron H N van Schaik
Journal: Invest New Drugs Date: 2005-12 Impact factor: 3.850

4. Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients.

Authors: Cynthia A Prows; Todd G Nick; Shannon N Saldaña; Sanjeev Pathak; Chunyan Liu; Kejian Zhang; Zachary S Daniels; Alexander A Vinks; Tracy A Glauser
Journal: J Child Adolesc Psychopharmacol Date: 2009-08 Impact factor: 2.576

5. Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects.

Authors: Martin T Ho; Edward J Kelly; Miklos Bodor; Tot Bui; Kris V Kowdley; Rodney J Y Ho
Journal: Ann Hepatol Date: 2011 Jul-Sep Impact factor: 2.400

6. Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.

Authors: A Gaedigk; A Bhathena; L Ndjountché; R E Pearce; S M Abdel-Rahman; S W Alander; L DiAnne Bradford; P K Rogan; J Steven Leeder
Journal: Pharmacogenomics J Date: 2005 Impact factor: 3.550

CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism.

1. BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors.

2. Identification of CYP2D6 impaired functional alleles in Mexican Americans.

Review 3. Cancer treatment and pharmacogenetics of cytochrome P450 enzymes.

4. Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients.

5. Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects.

6. Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.

7. Effect of a CYP2D6 polymorphism on the efficacy of donepezil in patients with Alzheimer disease.

8. Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

9. The pharmacokinetics of codeine and its metabolites in Blacks with sickle cell disease.

10. Semi-quantitative CYP2D6 gene doses in relation to metabolic ratios of psychotropics.