Literature DB >> 12762811

Sterol and triterpenoid constituents of Verbena littoralis with NGF-potentiating activity.

Yushan Li1, Masami Ishibashi, Masayuki Satake, Xigui Chen, Yasukatsu Oshima, Yasushi Ohizumi.   

Abstract

Two new sterols, stigmast-5-ene 3beta,4beta,7alpha,22alpha-tetraol (1) and stigmast-5-ene 3beta,7alpha,22alpha-triol (2), were isolated from the aerial parts of a Paraguayan medicinal plant, Verbena littoralis, together with the known compounds ursolic acid (3) and oleanolic acid (4). The structures of 1 and 2 were elucidated by spectroscopic analyses. Compounds 2-4 showed an enhancing activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells.

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Year:  2003        PMID： 12762811     DOI： 10.1021/np020577p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

Review 1.  Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae).

Authors:  Anita M Brinker; Jun Ma; Peter E Lipsky; Ilya Raskin
Journal:  Phytochemistry       Date:  2007-01-23       Impact factor: 4.072

Review 2.  Neurotrophic natural products: chemistry and biology.

Authors:  Jing Xu; Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  Angew Chem Int Ed Engl       Date:  2013-12-18       Impact factor: 15.336

3.  Microwave-assisted synthesis of 4-chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide (B-355252): a new potentiator of Nerve Growth Factor (NGF)-induced neurite outgrowth.

Authors:  Alfred L Williams; Srinivasa R Dandepally; Nailya Gilyazova; Sam M Witherspoon; Gordon Ibeanu
Journal:  Tetrahedron       Date:  2010-12-11       Impact factor: 2.457

4.  A synthetic analog of verbenachalcone potentiates NGF-induced neurite outgrowth and enhances cell survival in neuronal cell models.

Authors:  Ceiléssia M Clement; Srinivasa R Dandepally; Alfred L Williams; Gordon C Ibeanu
Journal:  Neurosci Lett       Date:  2009-05-07       Impact factor: 3.046

5.  Comparative antileishmanial efficacy of the biosynthesised ZnO NPs from genus Verbena.

Authors:  Muhammad Siddique Afridi; Syed Salman Hashmi; Gul Shad Ali; Muhammad Zia; Bilal Haider Abbasi
Journal:  IET Nanobiotechnol       Date:  2018-12       Impact factor: 1.847

6.  Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons.

Authors:  Hye-Ryeong Jo; Sung Eun Wang; Yong-Seok Kim; Chang Ho Lee; Hyeon Son
Journal:  Mol Cells       Date:  2017-06-30       Impact factor: 5.034

7.  Two New Cyathane Diterpenoids from Mycelial Cultures of the Medicinal Mushroom Hericium erinaceus and the Rare Species, Hericium flagellum.

Authors:  Zeljka Rupcic; Monique Rascher; Sae Kanaki; Reinhard W Köster; Marc Stadler; Kathrin Wittstein
Journal:  Int J Mol Sci       Date:  2018-03-06       Impact factor: 5.923

8.  Antioxidant activity against H2O2-induced cytotoxicity of the ethanol extract and compounds from Pyrola decorate leaves.

Authors:  Xiliang Yang; Qingyun Peng; Qian Liu; Jie Hu; Zhipeng Tang; Lianjie Cui; Zonghao Lin; Bing Xu; Kuojian Lu; Fang Yang; Zhizheng Sheng; Qiong Yuan; Song Liu; Jiuliang Zhang; Xuefeng Zhou
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

9.  Meliacarpinin-Type Limonoids from the Bark of Melia toosendan.

Authors:  Yalin Hu; Li Heng; Rong Xu; Junhe Li; Shanshan Wei; Deran Xu; Jun Luo; Yi Li
Journal:  Molecules       Date:  2018-10-10       Impact factor: 4.411

10.  3β, 6β-dichloro-5-hydroxy-5α-cholestane facilitates neuronal development through modulating TrkA signaling regulated proteins in primary hippocampal neuron.

Authors:  Md Abdul Hannan; Md Nazmul Haque; Raju Dash; Mahboob Alam; Il Soo Moon
Journal:  Sci Rep       Date:  2019-12-12       Impact factor: 4.379
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