Literature DB >> 12762808

New sesquiterpene quinols from a Micronesian sponge, Aka sp.

Venugopal J R V Mukku1, Ru A Edrada, Francis J Schmitz, Michelle Kelly Shanks, Babathosh Chaudhuri, Doriano Fabbro.   

Abstract

Three new sesquiterpene quinols (1, 2, and 5) and two known ones (3 and 4) were isolated along with halistanol sulfate (6) from a marine sponge of the genus Aka collected from Yap Island, Federated States of Micronesia. Their structures were determined from spectral data, and the structure of siphonodictyal C (3) was revised. Sulfates 3 and 6 inhibit CDK4/cyclin D1 complexation, whereas 1 and 4 do not.

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Year:  2003        PMID： 12762808     DOI： 10.1021/np0205506

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

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  3 in total

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