Literature DB >> 12762795

Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica.

Chia-Chung Hou1, Shwu-Jiuan Lin, Juei-Tang Cheng, Feng-Lin Hsu.   

Abstract

Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11beta,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.

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Year:  2003        PMID: 12762795     DOI: 10.1021/np0205349

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-09       Impact factor: 1.880

Review 2.  Antidiabetic plant-derived nutraceuticals: a critical review.

Authors:  Jayapal Naveen; Vallikannan Baskaran
Journal:  Eur J Nutr       Date:  2017-10-11       Impact factor: 5.614

3.  Furofuran lignans from a callus culture of Cichorium intybus.

Authors:  J Malarz; A Stojakowska; E Szneler; W Kisiel
Journal:  Plant Cell Rep       Date:  2005-04-05       Impact factor: 4.570

Review 4.  Antidiabetic phytoconstituents and their mode of action on metabolic pathways.

Authors:  Sudhanshu Kumar Bharti; Supriya Krishnan; Ashwini Kumar; Awanish Kumar
Journal:  Ther Adv Endocrinol Metab       Date:  2018-02-12       Impact factor: 3.565

5.  A cytotoxic dimeric furanoheliangolide from Piptocoma rufescens.

Authors:  Yulin Ren; Francisco Jiménez; Ricardo García; Milciades Mejía; Heebyung Chai; Norman R Farnsworth; Djaja D Soejarto; A Douglas Kinghorn
Journal:  Tetrahedron Lett       Date:  2013-10-02       Impact factor: 2.415

6.  Effects of the perinatal exposure of Gum Arabic on the development, behavior and biochemical parameters of mice offspring.

Authors:  May Binjumah; Jamaan Ajarem; Mohammad Ahmad
Journal:  Saudi J Biol Sci       Date:  2016-04-21       Impact factor: 4.219

Review 7.  The potential role of sesquiterpene lactones isolated from medicinal plants in the treatment of the metabolic syndrome - A review.

Authors:  Anuar Salazar-Gómez; Julio C Ontiveros-Rodríguez; Saudy S Pablo-Pérez; M Elena Vargas-Díaz; Leticia Garduño-Siciliano
Journal:  S Afr J Bot       Date:  2020-09-16       Impact factor: 2.315

  7 in total

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