Literature DB >> 12762694

Multivalent neoglycoconjugates by regiospecific cycloaddition of alkynes and azides using organic-soluble copper catalysts.

Francisco Pérez-Balderas1, Mariano Ortega-Muñoz, Julia Morales-Sanfrutos, Fernando Hernández-Mateo, Francisco G Calvo-Flores, Jose A Calvo-Asín, Joaquín Isac-García, Francisco Santoyo-González.   

Abstract

[reaction: see text] The construction of multivalent neoglycoconjugates is efficiently achieved by the regiospecific catalytic cycloaddition of alkynes and azides using the organic-soluble copper complexes (Ph(3)P)(3).CuBr and (EtO)(3)P.CuI. The simultaneous use of microwave irradiation shortened notably the reaction times.

Entities:  

Year:  2003        PMID： 12762694     DOI： 10.1021/ol034534r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  18 in total

1.  3'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations.

Authors:  Jay Lin; Vincent Roy; Liya Wang; Li You; Luigi A Agrofoglio; Dominique Deville-Bonne; Tamara R McBrayer; Steven J Coats; Raymond F Schinazi; Staffan Eriksson
Journal:  Bioorg Med Chem       Date:  2010-03-15       Impact factor: 3.641

2.  α-Azido ketones. Part 7: synthesis of 1,4-disubstituted triazoles by the "click" reaction of various terminal acetylenes with phenacyl azides or α-azidobenzo(hetera)cyclanones.

Authors:  Krisztina Kónya; Szabolcs Fekete; Anita Abrahám; Tamás Patonay
Journal:  Mol Divers       Date:  2012-02-04       Impact factor: 2.943

3.  Preparation of cyclodextrin chiral stationary phases by organic soluble catalytic 'click' chemistry.

Authors:  Yong Wang; Hui Chen; Yin Xiao; Cheong Hengq Ng; Ting Shan Oh; Timothy Thatt Yang Tan; Siu Choon Ng
Journal:  Nat Protoc       Date:  2011-06-09       Impact factor: 13.491

4.  Triazole bridges as versatile linkers in electron donor-acceptor conjugates.

Authors:  Gustavo de Miguel; Mateusz Wielopolski; David I Schuster; Michael A Fazio; Olivia P Lee; Christopher K Haley; Angy L Ortiz; Luis Echegoyen; Timothy Clark; Dirk M Guldi
Journal:  J Am Chem Soc       Date:  2011-07-27       Impact factor: 15.419

5.  "Click" conjugation of peptide on the surface of polymeric nanoparticles for targeting tumor angiogenesis.

Authors:  Stéphanie Deshayes; Victor Maurizot; Marie-Claude Clochard; Cécile Baudin; Thomas Berthelot; Stéphane Esnouf; Didier Lairez; Michel Moenner; Gérard Déléris
Journal:  Pharm Res       Date:  2011-03-04       Impact factor: 4.200

Review 6.  Carbohydrate polymers for nonviral nucleic acid delivery.

Authors:  Antons Sizovs; Patrick M McLendon; Sathya Srinivasachari; Theresa M Reineke
Journal:  Top Curr Chem       Date:  2010

Review 7.  Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides.

Authors:  Jason E Hein; Valery V Fokin
Journal:  Chem Soc Rev       Date:  2010-03-04       Impact factor: 54.564

8.  Vibrational stark effect probes for nucleic acids.

Authors:  Lisa N Silverman; Michael E Pitzer; Peter O Ankomah; Steven G Boxer; Edward E Fenlon
Journal:  J Phys Chem B       Date:  2007-09-18       Impact factor: 2.991

9.  Calix[4]arene-click-cyclodextrin and supramolecular structures with watersoluble NIPAAM-copolymers bearing adamantyl units: "Rings on ring on chain".

Authors:  Bernd Garska; Monir Tabatabai; Helmut Ritter
Journal:  Beilstein J Org Chem       Date:  2010-08-05       Impact factor: 2.883

Review 10.  Growing applications of "click chemistry" for bioconjugation in contemporary biomedical research.

Authors:  Kido Nwe; Martin W Brechbiel
Journal:  Cancer Biother Radiopharm       Date:  2009-06       Impact factor: 3.099
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