Immunoglobulins in endogenous uveitis.

Examination of 300 patients suffering from endogenous uveitis revealed raised levels of IgG in 24 per cent, IgA in 17 per cent, and IgM in 10 per cent. A raised level of one or more immunoglobulins was found more frequently in anterior uveitis than in the posterior form (44 compared with 24 per cent), in bilateral cases (47 compared with 35 per cent), and in relation to certain general diseases. No differences were demonstrated within the individual types of uveitis (fibrinous, nodular, etc.), nor was there any difference in prognosis (recurrence rate, visual impairment). Immunoglobulin levels were raised most often in elderly patients.