Literature DB >> 12760881

Eradication of resident bacteria of normal human skin by antimicrobial ointment.

J Owen Hendley1, Kathleen M Ashe.   

Abstract

The application of a topical triple-antibiotic ointment (containing neomycin, polymyxin, and bacitracin) eradicated resident bacteria through 25 layers of the stratum corneum and prevented repopulation of bacteria overnight but not at 1 week. Through 15 layers, mupirocin had some effect, whereas a double-antibiotic ointment had none. The reservoir of resident bacteria in the sebaceous glands is not affected by a topical antibiotic.

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Year:  2003        PMID： 12760881      PMCID： PMC155852          DOI： 10.1128/AAC.47.6.1988-1990.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  Effect of topical antimicrobial treatment on aerobic bacteria in the stratum corneum of human skin.

Authors:  J O Hendley; K M Ashe
Journal:  Antimicrob Agents Chemother       Date:  1991-04       Impact factor: 5.191

2.  Examination of the epidermis by the strip method of removing horny layers. I. Observations on thickness of the horny layer, and on mitotic activity after stripping.

Authors:  H PINKUS
Journal:  J Invest Dermatol       Date:  1951-06       Impact factor: 8.551

3.  Exploration of the microbial anatomy of normal human skin by using plasmid profiles of coagulase-negative staphylococci: search for the reservoir of resident skin flora.

Authors:  E Brown; R P Wenzel; J O Hendley
Journal:  J Infect Dis       Date:  1989-10       Impact factor: 5.226

4.  Contact dermatitis from neomycin and framycetin.

Authors:  V Kirton; D Munro-Ashman
Journal:  Lancet       Date:  1965-01-16       Impact factor: 79.321
  4 in total
  8 in total

1.  Penetration of chlorhexidine into human skin.

Authors:  T J Karpanen; T Worthington; B R Conway; A C Hilton; T S J Elliott; P A Lambert
Journal:  Antimicrob Agents Chemother       Date:  2008-08-01       Impact factor: 5.191

2.  Permeation of chlorhexidine from alcoholic and aqueous solutions within excised human skin.

Authors:  T J Karpanen; T Worthington; B R Conway; A C Hilton; T S J Elliott; P A Lambert
Journal:  Antimicrob Agents Chemother       Date:  2009-01-21       Impact factor: 5.191

3.  Distribution and visualisation of chlorhexidine within the skin using ToF-SIMS: a potential platform for the design of more efficacious skin antiseptic formulations.

Authors:  Amy M Judd; David J Scurr; Jon R Heylings; Ka-Wai Wan; Gary P Moss
Journal:  Pharm Res       Date:  2013-05-01       Impact factor: 4.200

4.  Reduced Bacterial Burden of the Skin Surrounding the Shoulder Joint Following Topical Protocatechuic Acid Application: Results of a Pilot Study.

Authors:  Omid Jalali; Molly Best; Alison Wong; Brett Schaeffer; Brendon Bauer; Lanny Johnson
Journal:  JB JS Open Access       Date:  2020-07-17

5.  Effect of the application of a bundle of three measures (intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples) on the surgical site infection after elective laparoscopic colorectal cancer surgery.

Authors:  Jaime Ruiz-Tovar; Carolina Llavero; Vicente Morales; Carlos Gamallo
Journal:  Surg Endosc       Date:  2018-01-18       Impact factor: 4.584

6.  Enhanced chlorhexidine skin penetration with eucalyptus oil.

Authors:  Tarja J Karpanen; Barbara R Conway; Tony Worthington; Anthony C Hilton; Tom S J Elliott; Peter A Lambert
Journal:  BMC Infect Dis       Date:  2010-09-22       Impact factor: 3.090

7.  Effect of Plant Extracts Formulated in Different Ointment Bases on MDR Strains.

Authors:  Pallavi L Pawar; Bela M Nabar
Journal:  Indian J Pharm Sci       Date:  2010-05       Impact factor: 0.975

8.  Bacteria induce skin regeneration via IL-1β signaling.

Authors:  Gaofeng Wang; Evan Sweren; Haiyun Liu; Eric Wier; Martin P Alphonse; Ruosi Chen; Nasif Islam; Ang Li; Yingchao Xue; Junjie Chen; Seungman Park; Yun Chen; Sam Lee; Yu Wang; Saifeng Wang; Nate K Archer; William Andrews; Maureen A Kane; Erika Dare; Sashank K Reddy; Zhiqi Hu; Elizabeth A Grice; Lloyd S Miller; Luis A Garza
Journal:  Cell Host Microbe       Date:  2021-04-01       Impact factor: 21.023
  8 in total

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