Literature DB >> 12759628

Interaction of all-trans-retinoic acid with fluconazole in acute promyelocytic leukemia.

Kelly L Vanier1, Andrea J Mattiussi, Donna L Johnston.   

Abstract

All-trans-retinoic acid (ATRA) has a dramatic antitumor effect in patients with acute promyelocytic leukemia (APL). It is hepatically metabolized by cytochrome P-450, and there are known toxicities associated with high levels of this drug. The effects of ATRA can be potentiated by inhibition of cytochrome P-450, which is known to occur with certain drugs. We report a case of a patient with ATRA toxicity thought to be secondary to interaction with fluconazole.

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Year:  2003        PMID： 12759628     DOI： 10.1097/00043426-200305000-00010

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN： 1077-4114            Impact factor:   1.289


  12 in total

1.  Pseudotumor Cerebri in Acute Promyelocytic Leukemia Patients on Intergroup Protocol 0129: Clinical Description and Recommendations for New Diagnostic Criteria.

Authors:  Catherine C Coombs; Lisa M DeAngelis; James H Feusner; Jacob M Rowe; Martin S Tallman
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2015-11-22

2.  The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid.

Authors:  Jayne E Thatcher; Alex Zelter; Nina Isoherranen
Journal:  Biochem Pharmacol       Date:  2010-05-31       Impact factor: 5.858

3.  Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.

Authors:  Jayne E Thatcher; Brian Buttrick; Scott A Shaffer; Jakob A Shimshoni; David R Goodlett; Wendel L Nelson; Nina Isoherranen
Journal:  Mol Pharmacol       Date:  2011-04-26       Impact factor: 4.436

Review 4.  The role of CYP26 enzymes in retinoic acid clearance.

Authors:  Jayne E Thatcher; Nina Isoherranen
Journal:  Expert Opin Drug Metab Toxicol       Date:  2009-08       Impact factor: 4.481

Review 5.  Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.

Authors:  Cara H Nelson; Brian R Buttrick; Nina Isoherranen
Journal:  Curr Top Med Chem       Date:  2013       Impact factor: 3.295

6.  Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases.

Authors:  Robert S Foti; Philippe Diaz; Dominique Douguet
Journal:  J Enzyme Inhib Med Chem       Date:  2016-07-17       Impact factor: 5.051

7.  Incidence of invasive aspergillosis following remission-induction chemotherapy for acute leukemia: a retrospective cohort study in a single Canadian tertiary care centre.

Authors:  Sapha Barkati; Simon F Dufresne; Sylvie Bélanger; Barbara Vadnais; Julie Bergeron; Annie Claude Labbé; Michel Laverdière
Journal:  CMAJ Open       Date:  2014-05-07

8.  All-Trans Retinoic Acid-Induced Pseudotumor Cerebri during Induction Therapy for Acute Promyelocytic Leukemia: A Case Report and Literature Review.

Authors:  Dylan Holmes; Prakash Vishnu; Russell K Dorer; David M Aboulafia
Journal:  Case Rep Oncol Med       Date:  2012-06-03

Review 9.  Safety of fluconazole in paediatrics: a systematic review.

Authors:  Oluwaseun Egunsola; Abiodun Adefurin; Apostolos Fakis; Evelyne Jacqz-Aigrain; Imti Choonara; Helen Sammons
Journal:  Eur J Clin Pharmacol       Date:  2013-01-17       Impact factor: 2.953

10.  All-trans-retinoic acid-induced pseudotumor cerebri in acute promyelocytic leukemia.

Authors:  T M Anoop; Nidhi Jain; Sreejith G Nair; Geetha Narayanan
Journal:  J Neurosci Rural Pract       Date:  2014-07
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