Literature DB >> 12756900

[Hepatic granulocytic sarcoma: an unusual presentation].

M A Alama Zaragoza1, A Robles Iniesta, I Roca Adelantado, M A Sales Maicas, A Ferrández Izquierdo, P Román Sánchez.   

Abstract

A case of granulocytic sarcoma (chloroma) of hepatic localization is presented. It is a extramedullary strange tumour, composed of immature precursors of myeloid cells. Clinically it can show, before, during or after a acute myeloid leukemia, chronic myeloproliferative disorders or myelodysplastic syndromes. Our patient, 81 year-old male, presented a process of important acute jaundice, with negative image technics, what indicated us the intrahepatic origin, negative tumorals markers, negative serology and hepatic biopsy (the piece of greenish coloration is described) what showed a hepatic sinusoides diffuse infiltration by indifferentiation cellularity, with study immuno-histochemical that was positive for the myeloperoxydase, giving a diagnose compatible with hepatic infiltration for acute myeloid leukemia. The patient doesn't present affectation of peripheral blood, and he died for acute hepatic and renal failure after 8 days of entrance.

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Mesh:

Year:  2003        PMID: 12756900

Source DB:  PubMed          Journal:  An Med Interna        ISSN: 0212-7199


  2 in total

1.  Massive myeloid sarcoma affecting the central nervous system, mediastinum, retroperitoneum, liver, and rectum associated with acute myeloblastic leukaemia: a case report.

Authors:  C R Best-Aguilera; M Vazquez-Del Mercado; J F Muñoz-Valle; L Herrera-Zarate; R E Navarro-Hernandez; B T Martin-Marquez; E Oregon-Romero; S Ruiz-Quezada; G M Bonilla; A Lomeli-Guerrero
Journal:  J Clin Pathol       Date:  2005-03       Impact factor: 3.411

2.  Collision diffuse large B cell lymphoma and myeloid sarcoma in the liver.

Authors:  Andrea Marra; Giovanni Martino; Nando Scarpelli; Vincenzo Perriello; Roberto Limongello; Stefano Ascani
Journal:  Ann Hematol       Date:  2020-08-28       Impact factor: 3.673

  2 in total

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