Literature DB >> 1275577

Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. II. Mature animals.

T Farkas, M Bihari-Varga, T Biró.   

Abstract

The effect of papain treatment on the cartilage tissue of the knee joint of mature rabbits was studied by histological and thermoanalytical methods. Changes taking place in the composition of cartilage in the course of ageing were shown. As a result of papain treatment a significant irreversible destruction of the ground substance took place. Papain-induced loss of proteoglycans and the intensity of repair reactions and age-related differences are discussed.

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Year:  1976        PMID: 1275577      PMCID: PMC1006501          DOI: 10.1136/ard.35.1.23

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  5 in total

1.  The Experimental Production of Arthritis: A Review.

Authors:  D L Gardner
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2.  Biochemical and metabolic abnormalities in osteoarthritic human cartilage.

Authors:  H J Mankin
Journal:  Fed Proc       Date:  1973-04

3.  Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. I. Immature animals.

Authors:  T Farkas; M Bihari-Varga; T Biró
Journal:  Ann Rheum Dis       Date:  1974-07       Impact factor: 19.103

4.  Thermoanalytical assay of glycosaminoglycans.

Authors:  M Bihari-Varga
Journal:  Acta Biochim Biophys Acad Sci Hung       Date:  1971

5.  Papain-induced degenerative arthritis of the hip in rabbits.

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Journal:  J Bone Joint Surg Br       Date:  1971-05
  5 in total
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6.  Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage.

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