Literature DB >> 1275562

Management of acute sulfide poisoning. Effects of oxygen, thiosulfate, and nitrite.

R P Smith, R Kruszyna, H Kruszyna.   

Abstract

Oxygen (100% at 1 atmosphere) did not protect mice against death from acute sulfide poisoning as compared with animals maintained under air at 1 atmosphere. Sodium thiosulfate had a small, but statistically significant (P less than .05) protective effect against death due to sodium sulfide, whether the mice were maintained under air or oxygen. Pretreatment with sodium nitrite, however, increased the acute intraperitoneal lethal dose for 50% survival of the group (LD50) of sodium sulfide 2.5 times. Neither oxygen, thiosulfate, nor the combination potentiated the protective effects of nitrite against sulfide poisoning. Antidotal effects of nitrite in acute sulfide poisoning were demonstrated in rats. The therapeutic efficacy of nitrite in acute poisoning is clearly superior to that of oxygen, which is the more widely recommended antidote.

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Year:  1976        PMID： 1275562     DOI： 10.1080/00039896.1976.10667212

Source DB:  PubMed          Journal:  Arch Environ Health        ISSN： 0003-9896


  14 in total

1.  Hydrogen sulfide poisoning.

Authors:  W W Burnett; E G King
Journal:  Can Med Assoc J       Date:  1978-04-08       Impact factor: 8.262

2.  Effects of infusion of human methemoglobin solution following hydrogen sulfide poisoning.

Authors:  B Chenuel; T Sonobe; P Haouzi
Journal:  Clin Toxicol (Phila)       Date:  2015-01-29       Impact factor: 4.467

3.  Kinetics and mechanism of the reaction of hydrogen sulfide with diaquacobinamide in aqueous solution.

Authors:  Denis S Salnikov; Sergei V Makarov; Rudi van Eldik; Polina N Kucherenko; Gerry R Boss
Journal:  Eur J Inorg Chem       Date:  2014-09       Impact factor: 2.524

4.  H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing.

Authors:  Candice M Klingerman; Neil Trushin; Bogdan Prokopczyk; Philippe Haouzi
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-07-31       Impact factor: 3.619

5.  Antagonism of Acute Sulfide Poisoning in Mice by Nitrite Anion without Methemoglobinemia.

Authors:  Andrea A Cronican; Kristin L Frawley; Humza Ahmed; Linda L Pearce; Jim Peterson
Journal:  Chem Res Toxicol       Date:  2015-06-08       Impact factor: 3.739

6.  Hydrogen sulfide poisoning: review of 5 years' experience.

Authors:  W W Burnett; E G King; M Grace; W F Hall
Journal:  Can Med Assoc J       Date:  1977-12-03       Impact factor: 8.262

7.  In vivo interactions between cobalt or ferric compounds and the pools of sulphide in the blood during and after H2S poisoning.

Authors:  Philippe Haouzi; Takashi Sonobe; Nicole Torsell-Tubbs; Bogdan Prokopczyk; Bruno Chenuel; Candice M Klingerman
Journal:  Toxicol Sci       Date:  2014-07-11       Impact factor: 4.849

8.  Methylene Blue Counteracts H2S-Induced Cardiac Ion Channel Dysfunction and ATP Reduction.

Authors:  Joseph Y Cheung; JuFang Wang; Xue-Qian Zhang; Jianliang Song; John M Davidyock; Fabian Jana Prado; Santhanam Shanmughapriya; Alison M Worth; Muniswamy Madesh; Annick Judenherc-Haouzi; Philippe Haouzi
Journal:  Cardiovasc Toxicol       Date:  2018-10       Impact factor: 3.231

Review 9.  International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors.

Authors:  Csaba Szabo; Andreas Papapetropoulos
Journal:  Pharmacol Rev       Date:  2017-10       Impact factor: 25.468

10.  On the Efficacy of Cardio-Pulmonary Resuscitation and Epinephrine Following Cyanide- and H2S Intoxication-Induced Cardiac Asystole.

Authors:  Annick Judenherc-HaouzI; Takashi Sonobe; Vikhyat S Bebarta; Philippe Haouzi
Journal:  Cardiovasc Toxicol       Date:  2018-10       Impact factor: 3.231
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