Literature DB >> 12754358

Mononeuritis multiplex in diabetes mellitus: evidence for underlying immune pathogenesis.

P Kelkar1, G J Parry.   

Abstract

Four patients with type 2 diabetes mellitus developed mononeuritis multiplex subacutely. Sural nerve biopsies showed multifocal axonal loss in all patients, with epineurial perivascular inflammation affecting small calibre vessels in three. Three patients improved with immunotherapy. These observations suggest that mononeuritis multiplex in diabetes may be caused by an immune mediated vasculopathy and that it is pathogenetically akin to the more common and better recognised diabetic amyotrophy.

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Year:  2003        PMID： 12754358      PMCID： PMC1738474          DOI： 10.1136/jnnp.74.6.803

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  5 in total

1.  Diabetic amyotrophy, not your typical back pain.

Authors:  Jonathan Seung Doe Na; Philip C Dittmar
Journal:  BMJ Case Rep       Date:  2020-01-09

2.  Nerve biopsy findings contribute to diagnosis of multiple mononeuropathy: 78% of findings support clinical diagnosis.

Authors:  Ying-Shuang Zhang; A-Ping Sun; Lu Chen; Rong-Fang Dong; Yan-Feng Zhong; Jun Zhang
Journal:  Neural Regen Res       Date:  2015-01       Impact factor: 5.135

3.  Hemifacial Spasm as the Presenting Manifestation of Type 3c Diabetes Mellitus.

Authors:  Ritwik Ghosh; Dipayan Roy; Subhankar Chatterjee; Souvik Dubey; Bikash Chandra Swaika; Arpan Mandal; Julián Benito-León
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2021-04-26

4.  Recrudescence of severe polyneuropathy after receiving Pfizer-BioNTech COVID-19 vaccine in a patient with a history of eosinophilic granulomatosis with polyangiitis.

Authors:  Rahul Gill; Macym Rizvi; Muhammad S Sadiq; Mark Feldman
Journal:  BMJ Case Rep       Date:  2022-04-29

5.  A man with small vessel vasculitis presenting with brachial diplegia, multiple cranial mononeuropathies and severe orthostatic hypotension in diabetes mellitus: a case report.

Authors:  Sahar F Zafar; Jerry Clay Goodman; Eroboghene E Ubogu
Journal:  J Med Case Rep       Date:  2013-10-01
  5 in total

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