Literature DB >> 12753413

Impact of five cytochrome p450 enzymes on the metabolism of two heterocyclic aromatic amines, 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC).

Hanne Frederiksen1, Henrik Frandsen.   

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Year:  2003        PMID： 12753413     DOI： 10.1034/j.1600-0773.2003.920508.x

Source DB:  PubMed          Journal:  Pharmacol Toxicol        ISSN： 0901-9928


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  6 in total

1.  UDP-glucuronosyltransferase-mediated metabolic activation of the tobacco carcinogen 2-amino-9H-pyrido[2,3-b]indole.

Authors:  Yijin Tang; David M LeMaster; Gwendoline Nauwelaërs; Dan Gu; Sophie Langouët; Robert J Turesky
Journal:  J Biol Chem       Date:  2012-03-05       Impact factor: 5.157

2.  Evaluation of Tobacco Smoke and Diet as Sources of Exposure to Two Heterocyclic Aromatic Amines for the U.S. Population: NHANES 2013-2014.

Authors:  Li Zhang; Lanqing Wang; Yao Li; Yang Xia; Cindy M Chang; Baoyun Xia; Connie S Sosnoff; Brittany N Pine; B Rey deCastro; Benjamin C Blount
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2019-10-01       Impact factor: 4.254

Review 3.  Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines.

Authors:  Robert J Turesky; Loic Le Marchand
Journal:  Chem Res Toxicol       Date:  2011-06-20       Impact factor: 3.739

4.  DNA adduct formation of 4-aminobiphenyl and heterocyclic aromatic amines in human hepatocytes.

Authors:  Gwendoline Nauwelaers; Erin E Bessette; Dan Gu; Yijin Tang; Julie Rageul; Valérie Fessard; Jian-Min Yuan; Mimi C Yu; Sophie Langouët; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2011-04-19       Impact factor: 3.739

5.  The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole.

Authors:  Robert J Turesky; Jean Bendaly; Isil Yasa; Mark A Doll; David W Hein
Journal:  Chem Res Toxicol       Date:  2009-04       Impact factor: 3.739

6.  Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice.

Authors:  Robert J Turesky; Dmitri Konorev; Xiaoyu Fan; Yijin Tang; Lihua Yao; Xinxin Ding; Fang Xie; Yi Zhu; Qing-Yu Zhang
Journal:  Chem Res Toxicol       Date:  2015-12-03       Impact factor: 3.739
  6 in total

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