Literature DB >> 12750543

Impact of establishing a primary stroke center at a community hospital on the use of thrombolytic therapy: the NINDS Suburban Hospital Stroke Center experience.

Susan Unipan Lattimore1, Julio Chalela, Lisa Davis, Thomas DeGraba, Mustapha Ezzeddine, Joseph Haymore, Paul Nyquist, Alison E Baird, John Hallenbeck, Steven Warach.   

Abstract

BACKGROUND AND
PURPOSE: To increase the proportion of ischemic stroke patients treated with thrombolytic therapy, the establishment of primary stroke centers in community hospitals has been advocated. We evaluated the use of thrombolytic therapy before and after institution of a primary stroke center in a community hospital.
METHODS: The availability of an on-call stroke emergency response team was the only significant additional resource required for this hospital. All eligible patients were treated with intravenous tissue plasminogen activator (tPA). The number of patients with cerebrovascular disease, number and proportion of patients treated with tPA, times to treatment, and patient outcomes were recorded during the first 2 years of the stroke center.
RESULTS: During the 12 months before institution of the stroke center, 3 ischemic stroke patients (1.5%) were treated with tPA. During the 2-year period of around-the-clock coverage, 44 of 420 ischemic stroke patients (10.5%) were treated with intravenous tPA, a significant increase in tPA use (P<0.0001).
CONCLUSIONS: Establishment of a primary stroke center at a community hospital resulted in a substantial increase in the proportion of patients receiving thrombolytic therapy for ischemic stroke. If this experience is generalized, the beneficial impact of primary stroke centers on stroke outcomes and costs to the healthcare system may be substantial.

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Year:  2003        PMID: 12750543     DOI: 10.1161/01.STR.0000073789.12120.F3

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  26 in total

Review 1.  Mechanical interventions to treat acute stroke.

Authors:  David Fussell; H Christian Schumacher; Philip M Meyers; Randall T Higashida
Journal:  Curr Neurol Neurosci Rep       Date:  2007-01       Impact factor: 5.081

2.  Telemedicine is crucial to implementing acute stroke therapy.

Authors:  Sean I Savitz
Journal:  MedGenMed       Date:  2006-02-06

Review 3.  Intravenous thrombolysis in acute ischaemic stroke: optimising its use in routine clinical practice.

Authors:  Dawn M Bravata
Journal:  CNS Drugs       Date:  2005       Impact factor: 5.749

4.  Reperfusion half-life: a novel pharmacodynamic measure of thrombolytic activity.

Authors:  José G Merino; Lawrence L Latour; Li An; Amie W Hsia; Dong-Wha Kang; Steven Warach
Journal:  Stroke       Date:  2008-05-01       Impact factor: 7.914

5.  Outcomes after ischemic stroke for hospitals with and without Joint Commission-certified primary stroke centers.

Authors:  J H Lichtman; S B Jones; Y Wang; E Watanabe; E Leifheit-Limson; L B Goldstein
Journal:  Neurology       Date:  2011-05-04       Impact factor: 9.910

6.  Potential synergy between advanced primary stroke centers and level I or II trauma centers in the United States.

Authors:  Asif A Khan; Saqib A Chaudhry; Ameer E Hassan; Gustavo J Rodriguez; M Fareed K Suri; Kamakshi Lakshminarayan; Adnan I Qureshi
Journal:  Am J Emerg Med       Date:  2012-03-16       Impact factor: 2.469

Review 7.  Development of regional stroke programs.

Authors:  Adam de Havenon; Ali Sultan-Qurraie; Peter Hannon; David Tirschwell
Journal:  Curr Neurol Neurosci Rep       Date:  2015-05       Impact factor: 5.081

8.  Advanced modality imaging evaluation in acute ischemic stroke may lead to delayed endovascular reperfusion therapy without improvement in clinical outcomes.

Authors:  Kevin N Sheth; John B Terry; Raul G Nogueira; Anat Horev; Thanh N Nguyen; Albert K Fong; Dheeraj Gandhi; Shyam Prabhakaran; Dolora Wisco; Brenda A Glenn; Ashis H Tayal; Bryan Ludwig; Muhammad Shazam Hussain; Tudor G Jovin; Paul F Clemmons; Carolyn Cronin; David S Liebeskind; Melissa Tian; Rishi Gupta
Journal:  J Neurointerv Surg       Date:  2012-10-16       Impact factor: 5.836

Review 9.  Therapeutic time window of thrombolytic therapy following stroke.

Authors:  Peter D Schellinger; Steven Warach
Journal:  Curr Atheroscler Rep       Date:  2004-07       Impact factor: 5.113

10.  Joint Commission primary stroke center certification does not affect proband enrollment: the siblings with ischemic stroke study.

Authors:  Alexa N Richie; Jorge Trejo; Christian G Bowers; Rebecca B McNeil; Dale M Gamble; Sothear H Luke; Robert D Brown; Thomas G Brott; Brett M Kissela; Bradford B Worrall; James F Meschia
Journal:  J Stroke Cerebrovasc Dis       Date:  2009 Sep-Oct       Impact factor: 2.136

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