Literature DB >> 12750449

Functional modulation of the sodium pump: the regulatory proteins "Fixit".

Flemming Cornelius1, Yasser A Mahmmoud.   

Abstract

Proteins of the FXYD family act as tissue-specific regulators of the Na-K-ATPase. They are small hydrophobic type I proteins with a single-transmembrane span containing an extracellular invariant FXYD sequence. FXYD proteins are not an integral part of the Na-K-ATPase but function to modulate its catalytic properties by molecular interactions with specific Na-K-ATPase domains.

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Year:  2003        PMID： 12750449     DOI： 10.1152/nips.01434.2003

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  22 in total

1.  Kinetics of K(+) occlusion by the phosphoenzyme of the Na(+),K(+)-ATPase.

Authors:  Sian L Myers; Flemming Cornelius; Hans-Jürgen Apell; Ronald J Clarke
Journal:  Biophys J       Date:  2011-01-05       Impact factor: 4.033

2.  Amino acid substitutions in the FXYD motif enhance phospholemman-induced modulation of cardiac L-type calcium channels.

Authors:  Kai Guo; Xianming Wang; Guofeng Gao; Congxin Huang; Keith S Elmslie; Blaise Z Peterson
Journal:  Am J Physiol Cell Physiol       Date:  2010-08-18       Impact factor: 4.249

3.  Curcumin modulation of Na,K-ATPase: phosphoenzyme accumulation, decreased K+ occlusion, and inhibition of hydrolytic activity.

Authors:  Yasser A Mahmmoud
Journal:  Br J Pharmacol       Date:  2005-05       Impact factor: 8.739

4.  Structure of the Na,K-ATPase regulatory protein FXYD1 in micelles.

Authors:  Peter Teriete; Carla M Franzin; Jungyuen Choi; Francesca M Marassi
Journal:  Biochemistry       Date:  2007-05-19       Impact factor: 3.162

Review 5.  Structures of the FXYD regulatory proteins in lipid micelles and membranes.

Authors:  Carla M Franzin; Xiao-Min Gong; Peter Teriete; Francesca M Marassi
Journal:  J Bioenerg Biomembr       Date:  2007-12       Impact factor: 2.945

6.  Na+/K+-ATPase response to salinity change and its correlation with FXYD11 expression in Anguilla marmorata.

Authors:  Fenfei Liang; Li Li; Guosong Zhang; Shaowu Yin; Xiaolu Wang; Peng Li; Yihe Jia; Yayuan Wang; Li Wang; Xiaojun Wang
Journal:  J Comp Physiol B       Date:  2017-03-09       Impact factor: 2.200

7.  Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.

Authors:  Neeraj Kumar Mishra; Michael Habeck; Corinna Kirchner; Haim Haviv; Yoav Peleg; Miriam Eisenstein; Hans Juergen Apell; Steven J D Karlish
Journal:  J Biol Chem       Date:  2015-10-01       Impact factor: 5.157

8.  Structure of the Na,K-ATPase regulatory protein FXYD2b in micelles: implications for membrane-water interfacial arginines.

Authors:  Xiao-Min Gong; Yi Ding; Jinghua Yu; Yong Yao; Francesca M Marassi
Journal:  Biochim Biophys Acta       Date:  2014-05-02

9.  Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1.

Authors:  Peter Teriete; Khang Thai; Jungyuen Choi; Francesca M Marassi
Journal:  Biochim Biophys Acta       Date:  2009-09-15

10.  Membrane orientation of the Na,K-ATPase regulatory membrane protein CHIF determined by solid-state NMR.

Authors:  Carla M Franzin; Peter Teriete; Francesca M Marassi
Journal:  Magn Reson Chem       Date:  2007-12       Impact factor: 2.447
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