| Literature DB >> 12749411 |
M Rajbhandari1, U Wegner, T Schöpke, U Lindequist, R Mentel.
Abstract
Methanol water extract from rhizomes of Bergenia ligulata, a plant used in Nepalese ethnomedicine, inhibited in vitro the replication of influenza virus in a dose dependent manner and did not show virucidal activity at effective concentration. Pretreatment of cells with B. ligulata extract was shown to be most effective to prevent cell destruction. The extract inhibited viral RNA synthesis and reduced viral peptide synthesis at 10 microg/ml. The virus inhibitory effect is related to the presence of condensed tannins in the extract.Entities:
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Year: 2003 PMID: 12749411
Source DB: PubMed Journal: Pharmazie ISSN: 0031-7144 Impact factor: 1.267