Literature DB >> 12748654

Control of osteoblast function and regulation of bone mass.

Shun-ichi Harada1, Gideon A Rodan.   

Abstract

The skeleton is an efficient 'servo' (feedback-controlled/steady-state) system that continuously integrates signals and responses which sustain its functions of delivering calcium while maintaining strength. In many individuals, bone mass homeostasis starts failing in midlife, leading to bone loss, osteoporosis and debilitating fractures. Recent advances, spearheaded by genetic information, offer the opportunity to stop or reverse this downhill course.

Entities:  

Mesh：

Year:  2003        PMID： 12748654     DOI： 10.1038/nature01660

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  379 in total

1.  Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo.

Authors:  Helmut Glantschnig; Richard A Hampton; Ping Lu; Jing Z Zhao; Salvatore Vitelli; Lingyi Huang; Peter Haytko; Tara Cusick; Cheryl Ireland; Stephen W Jarantow; Robin Ernst; Nan Wei; Pascale Nantermet; Kevin R Scott; John E Fisher; Fabio Talamo; Laura Orsatti; Alfred A Reszka; Punam Sandhu; Donald Kimmel; Osvaldo Flores; William Strohl; Zhiqiang An; Fubao Wang
Journal:  J Biol Chem       Date:  2010-10-07       Impact factor: 5.157

2.  Enhanced affinity bifunctional bisphosphonates for targeted delivery of therapeutic agents to bone.

Authors:  Jivan N Yewle; David A Puleo; Leonidas G Bachas
Journal:  Bioconjug Chem       Date:  2011-12-05       Impact factor: 4.774

3.  The beneficial effect of Radix Dipsaci total saponins on bone metabolism in vitro and in vivo and the possible mechanisms of action.

Authors:  Y B Niu; Y H Li; X H Kong; R Zhang; Y Sun; Q Li; C Li; L Liu; J Wang; Q B Mei
Journal:  Osteoporos Int       Date:  2012-04-26       Impact factor: 4.507

4.  c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression.

Authors:  Hui-Yi Kua; Huijuan Liu; Wai Fook Leong; Lili Li; Deyong Jia; Gang Ma; Yuanyu Hu; Xueying Wang; Jenny F L Chau; Ye-Guang Chen; Yuji Mishina; Sharon Boast; James Yeh; Li Xia; Guo-Qiang Chen; Lin He; Stephen P Goff; Baojie Li
Journal:  Nat Cell Biol       Date:  2012-06-24       Impact factor: 28.824

5.  Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

Authors:  Harikiran Nistala; Sui Lee-Arteaga; Silvia Smaldone; Gabriella Siciliano; Francesco Ramirez
Journal:  J Biol Chem       Date:  2010-08-21       Impact factor: 5.157

Review 6.  Glucocorticoid-Induced Osteoporosis.

Authors:  Baruch Frenkel; Wendy White; Jan Tuckermann
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

Review 7.  Genetics of metastasis: melanoma and other cancers.

Authors:  Noel Turner; Olivia Ware; Marcus Bosenberg
Journal:  Clin Exp Metastasis       Date:  2018-05-02       Impact factor: 5.150

8.  Deletion of ferroportin in murine myeloid cells increases iron accumulation and stimulates osteoclastogenesis in vitro and in vivo.

Authors:  Lei Wang; Bin Fang; Toshifumi Fujiwara; Kimberly Krager; Akshita Gorantla; Chaoyuan Li; Jian Q Feng; Michael L Jennings; Jian Zhou; Nukhet Aykin-Burns; Haibo Zhao
Journal:  J Biol Chem       Date:  2018-05-03       Impact factor: 5.157

9.  N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.

Authors:  Eric Haÿ; Emmanuel Laplantine; Valérie Geoffroy; Monique Frain; Thomas Kohler; Ralph Müller; Pierre J Marie
Journal:  Mol Cell Biol       Date:  2008-12-15       Impact factor: 4.272

10.  PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.

Authors:  Tomohiro Hikata; Hironari Takaishi; Jiro Takito; Akihiro Hakozaki; Mitsuru Furukawa; Shinichi Uchikawa; Tokuhiro Kimura; Yasunori Okada; Masahito Matsumoto; Akihiko Yoshimura; Riko Nishimura; Sakamuri V Reddy; Hiroshi Asahara; Yoshiaki Toyama
Journal:  Blood       Date:  2008-10-24       Impact factor: 22.113
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.