Literature DB >> 12748564

Oncologic and functional results of near-total laryngectomy.

Ricardo Bernáldez1, Marta García-Pallarés, Eduardo Morera, Luis Lassaletta, Antonio Del Palacio, Javier Gavilán.   

Abstract

OBJECTIVE: To report the oncologic and functional outcome of patients undergoing near-total laryngectomy. STUDY DESIGN AND
SETTING: A retrospective analysis was carried out from 1991 through 1998.
RESULTS: Eighty-seven patients underwent near-total laryngectomy. The Kaplan-Meier overall survival, cause-specific survival, and relapse-free survival estimates at 5 years were 48.2%, 75.8%, and 72.4%, respectively. Univariate analysis revealed prognosis significance for location, stage, and pathologic cervical lymph node status. Five percent of the patients developed local recurrence, 16% recurrence in cervical lymph nodes, and 10% distant metastasis. Pharyngocutaneous fistula was the most frequent complication (48%). Seventy-seven percent of cases achieved voice preservation. Symptomatic aspiration was noted in 12.3% of cases.
CONCLUSION: Near-total laryngectomy can be a successful surgical procedure for selected patients; it does not replace total laryngectomy but reduces its indications. Voice preservation can be achieved in most cases. SIGNIFICANCE: Near-total laryngectomy enhances the speech rehabilitation options for the laryngectomy patient by adding a physiologic, nonprosthetic tissue technique.

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Year:  2003        PMID: 12748564     DOI: 10.1016/S0194-59980300095-0

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  3 in total

1.  Post laryngectomy speech rehabilitation outcome in elderly patients.

Authors:  Salvatore Cocuzza; Marco Bonfiglio; Calogero Grillo; Luigi Maiolino; Mariano Malaguarnera; Francesco Martines; Agostino Serra
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-03-22       Impact factor: 2.503

2.  Functional outcomes of patients with advanced pyriform sinus cancer treated with extended near-total laryngopharyngectomy and free fasciocutaneous flap reconstruction.

Authors:  Pei-Yin Wu; Yur-Ren Kuo; Seng-Feng Jeng; Cheng-Ming Hsu; Chih-Ying Su
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-06-26       Impact factor: 2.503

3.  Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma.

Authors:  Xue-Kui Liu; Xin-Rui Zhang; Qian Zhong; Man-Zhi Li; Zhi-Min Liu; Zhi-Rui Lin; Di Wu; Mu-Sheng Zeng
Journal:  J Transl Med       Date:  2013-03-07       Impact factor: 5.531

  3 in total

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