Dennis C Szurkus1, Terry A Harrison. 1. Division of Gynecologic Oncology, Naval Medical Center, PSC 1003 Box 8, San Diego FPO AE, CA 09728, USA.
Abstract
OBJECTIVE: Our purpose was to examine the correlation between colposcopic and histologic findings in patients who have undergone loop electrosurgical excision of the cervix (LEEP) for high-grade dysplasia on cytology without prior colposcopically directed biopsy. STUDY DESIGN: A retrospective review was performed of all patients who underwent LEEP for high-grade squamous intraepithelial lesion (HGSIL) on Papanicolaou (Pap) smear without a prior cervical biopsy over a 17-month period. We correlated the histologic result with colposcopic findings at the time of LEEP. RESULTS: Of 104 patients undergoing LEEP, 63 patients (61%) had cervical intraepithelial neoplasia (CIN) grade 2 or greater. Thirty-four (54%) of these 63 patients with histologically proved high-grade dysplasia had a normal or low-grade colposcopic examination. There were 10 patients with CIN 1 to CIN 1-2 and 1 patient with microinvasive squamous cell carcinoma. CONCLUSION: Despite lack of correlation between colposcopic and histologic results, HGSIL on Pap smear is an appropriate indication for LEEP.
OBJECTIVE: Our purpose was to examine the correlation between colposcopic and histologic findings in patients who have undergone loop electrosurgical excision of the cervix (LEEP) for high-grade dysplasia on cytology without prior colposcopically directed biopsy. STUDY DESIGN: A retrospective review was performed of all patients who underwent LEEP for high-grade squamous intraepithelial lesion (HGSIL) on Papanicolaou (Pap) smear without a prior cervical biopsy over a 17-month period. We correlated the histologic result with colposcopic findings at the time of LEEP. RESULTS: Of 104 patients undergoing LEEP, 63 patients (61%) had cervical intraepithelial neoplasia (CIN) grade 2 or greater. Thirty-four (54%) of these 63 patients with histologically proved high-grade dysplasia had a normal or low-grade colposcopic examination. There were 10 patients with CIN 1 to CIN 1-2 and 1 patient with microinvasive squamous cell carcinoma. CONCLUSION: Despite lack of correlation between colposcopic and histologic results, HGSIL on Pap smear is an appropriate indication for LEEP.
Authors: Michelle I Silver; Jeff Andrews; Charles K Cooper; Julia C Gage; Michael A Gold; Michelle J Khan; L Stewart Massad; Valentin Parvu; Rebecca B Perkins; Mark Schiffman; Katie M Smith; Nicolas Wentzensen Journal: Obstet Gynecol Date: 2018-09 Impact factor: 7.661
Authors: Hannah P Yang; Rosemary E Zuna; Mark Schiffman; Joan L Walker; Mark E Sherman; Lisa M Landrum; Katherine Moxley; Michael A Gold; S Terence Dunn; Richard A Allen; Roy Zhang; Rodney Long; Sophia S Wang; Nicolas Wentzensen Journal: PLoS One Date: 2012-01-13 Impact factor: 3.240