BACKGROUND AND PURPOSE: Dysembryoplastic neuroepithelial tumors (DNTs) are benign lesions affecting children and are associated with epilepsy. The goal of our study was to better characterize the clinical-radiologic-pathologic spectrum of DNTs (complex and simple forms only) in a series of 14 children. METHODS: Clinical, neuroradiologic, and pathologic features of all cases were retrospectively studied. RESULTS: Eleven cases of complex and three cases of simple DNTs were identified. Mean follow-up was 87 months, and no recurrence was recorded except for one case of simple DNT. We found that some neuroradiologic features may be helpful to support the diagnosis of DNT: presence of "septations," triangular pattern of distribution, and absence of contrast enhancement. CONCLUSION: The evidence of the specific glioneuronal element is found by pathologic examination, but the typical neuroradiologic aspect of DNT suggests this diagnosis preoperatively. Radiologic examination may be helpful for the diagnosis of DNT when pathologic findings are inconclusive.
BACKGROUND AND PURPOSE:Dysembryoplastic neuroepithelial tumors (DNTs) are benign lesions affecting children and are associated with epilepsy. The goal of our study was to better characterize the clinical-radiologic-pathologic spectrum of DNTs (complex and simple forms only) in a series of 14 children. METHODS: Clinical, neuroradiologic, and pathologic features of all cases were retrospectively studied. RESULTS: Eleven cases of complex and three cases of simple DNTs were identified. Mean follow-up was 87 months, and no recurrence was recorded except for one case of simple DNT. We found that some neuroradiologic features may be helpful to support the diagnosis of DNT: presence of "septations," triangular pattern of distribution, and absence of contrast enhancement. CONCLUSION: The evidence of the specific glioneuronal element is found by pathologic examination, but the typical neuroradiologic aspect of DNT suggests this diagnosis preoperatively. Radiologic examination may be helpful for the diagnosis of DNT when pathologic findings are inconclusive.
Authors: M Thom; B Gomez-Anson; T Revesz; W Harkness; C J O'Brien; R Kett-White; E W Jones; J Stevens; F Scaravilli Journal: J Neurol Neurosurg Psychiatry Date: 1999-07 Impact factor: 10.154
Authors: A A Raymond; S F Halpin; N Alsanjari; M J Cook; N D Kitchen; D R Fish; J M Stevens; B N Harding; F Scaravilli; B Kendall Journal: Brain Date: 1994-06 Impact factor: 13.501
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Authors: Phillip A Bonney; Lillian B Boettcher; Andrew K Conner; Chad A Glenn; Robert G Briggs; Joshua A Santucci; Michael R Bellew; James D Battiste; Michael E Sughrue Journal: J Neurooncol Date: 2015-10-29 Impact factor: 4.130