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18 in total

1. State dependent dissociation of HERG channel inhibitors.

Authors: D Stork; E N Timin; S Berjukow; C Huber; A Hohaus; M Auer; S Hering
Journal: Br J Pharmacol Date: 2007-06-25 Impact factor: 8.739

2. Shape signatures: new descriptors for predicting cardiotoxicity in silico.

Authors: Dmitriy S Chekmarev; Vladyslav Kholodovych; Konstantin V Balakin; Yan Ivanenkov; Sean Ekins; William J Welsh
Journal: Chem Res Toxicol Date: 2008-05-08 Impact factor: 3.739

3. Cardio-vascular safety beyond hERG: in silico modelling of a guinea pig right atrium assay.

Authors: Luca A Fenu; Ard Teisman; Stefan S De Buck; Vikash K Sinha; Ron A H J Gilissen; Marjoleen J M A Nijsen; Claire E Mackie; Wendy E Sanderson
Journal: J Comput Aided Mol Des Date: 2009-11-05 Impact factor: 3.686

4. Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation.

Authors: Shawn P Walsh; Aurash Shahripour; Haifeng Tang; Nardos Teumelsan; Jessica Frie; Yuping Zhu; Birgit T Priest; Andrew M Swensen; Jessica Liu; Michael Margulis; Richard Visconti; Adam Weinglass; John P Felix; Richard M Brochu; Timothy Bailey; Brande Thomas-Fowlkes; Magdalena Alonso-Galicia; Xiaoyan Zhou; Lee-Yuh Pai; Aaron Corona; Caryn Hampton; Melba Hernandez; Ross Bentley; Jing Chen; Kashmira Shah; Joseph Metzger; Michael Forrest; Karen Owens; Vincent Tong; Sookhee Ha; Sophie Roy; Gregory J Kaczorowski; Lihu Yang; Emma Parmee; Maria L Garcia; Kathleen Sullivan; Alexander Pasternak
Journal: ACS Med Chem Lett Date: 2015-05-07 Impact factor: 4.345

5. Comparative study of the structure and interaction of the pore helices of the hERG and Kv1.5 potassium channels in model membranes.

Authors: Maïwenn Beaugrand; Alexandre A Arnold; Steve Bourgault; Philip T F Williamson; Isabelle Marcotte
Journal: Eur Biophys J Date: 2017-03-17 Impact factor: 1.733

6. Novel Bayesian classification models for predicting compounds blocking hERG potassium channels.

Authors: Li-li Liu; Jing Lu; Yin Lu; Ming-yue Zheng; Xiao-min Luo; Wei-liang Zhu; Hua-liang Jiang; Kai-xian Chen
Journal: Acta Pharmacol Sin Date: 2014-06-30 Impact factor: 6.150

7. 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides.

Authors: Marvin J Meyers; Jianguang Liu; Jing Xu; Fang Leng; Jiantong Guan; Zhijun Liu; Sarah A McNitt; Limei Qin; Linglin Dai; Hongwei Ma; Dickson Adah; Siting Zhao; Xiaofen Li; Alex J Polino; Armiyaw S Nasamu; Daniel E Goldberg; Xiaorong Liu; Yongzhi Lu; Zhengchao Tu; Xiaoping Chen; Micky D Tortorella
Journal: J Med Chem Date: 2019-03-22 Impact factor: 7.446

8. Proarrhythmic mechanisms of the common anti-diarrheal medication loperamide: revelations from the opioid abuse epidemic.

Authors: Jiesheng Kang; David R Compton; Roy J Vaz; David Rampe
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2016-08-16 Impact factor: 3.000

Review 9. HERG1 channel agonists and cardiac arrhythmia.

Authors: Michael C Sanguinetti
Journal: Curr Opin Pharmacol Date: 2013-11-27 Impact factor: 5.547

Review 10. Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective.

Authors: C E Pollard; J-P Valentin; T G Hammond
Journal: Br J Pharmacol Date: 2008-05-26 Impact factor: 8.739