| Literature DB >> 12746396 |
B C Hendrickson1, D Pruss, E Lyon, T Scholl.
Abstract
An expectation maximisation based prediction algorithm was created to identify unusual haplotypes in patient samples that may be caused by small intragenic deletions. In this approach, unphased SNP genotypes are compared to pairs of canonical haplotypes to identify potentially hemizygous regions. This method was successfully applied to identify five deletions in the 3' region of BRCA1.Entities:
Mesh：
Year: 2003 PMID： 12746396 PMCID： PMC1735469 DOI： 10.1136/jmg.40.5.346
Source DB: PubMed Journal: J Med Genet ISSN： 0022-2593 Impact factor: 6.318