Literature DB >> 12744325

A novel peptide synthesis using fluorous chemistry.

Mamoru Mizuno1, Kohtaro Goto, Tsuyoshi Miura, Daisuke Hosaka, Toshiyuki Inazu.   

Abstract

Three new fluorous supports for peptide synthesis, i.e., the trialkoxybenzhydryl-type (6), the Wang-type (7) and the tert-butyl-type support (8), were prepared. A bioactive peptide TRH was easily synthesized by an Fmoc strategy using the benzhydryl-type fluorous support with fluorous chemistry.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12744325     DOI： 10.1039/b300682d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  Fluorous tagging strategy for solution-phase synthesis of small molecules, peptides and oligosaccharides.

Authors:  Wei Zhang
Journal:  Curr Opin Drug Discov Devel       Date:  2004-11

2.  Fluorous mixture synthesis of two libraries with hydantoin-, and benzodiazepinedione-fused heterocyclic scaffolds.

Authors:  Wei Zhang; Yimin Lu; Christine Hiu-Tung Chen; Lu Zeng; Daniel B Kassel
Journal:  J Comb Chem       Date:  2006 Sep-Oct

3.  Fluorous Synthesis of Hydantoin-, Piperazinedione-, and Benzodiazepinedione-Fused Tricyclic and Tetracyclic Ring Systems.

Authors:  Wei Zhang; Yimin Lu; Christine Hiu-Tung Chen; Dennis P Curran; Steven Geib
Journal:  European J Org Chem       Date:  2006

4.  AJIPHASE®: A Highly Efficient Synthetic Method for One-Pot Peptide Elongation in the Solution Phase by an Fmoc Strategy.

Authors:  Daisuke Takahashi; Tatsuji Inomata; Tatsuya Fukui
Journal:  Angew Chem Int Ed Engl       Date:  2017-06-07       Impact factor: 15.336

Review 5.  Ionic liquid applications in peptide chemistry: synthesis, purification and analytical characterization processes.

Authors:  Alesia A Tietze; Pascal Heimer; Annegret Stark; Diana Imhof
Journal:  Molecules       Date:  2012-04-05       Impact factor: 4.411

6.  Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides.

Authors:  Chao Cai; Demetria M Dickinson; Lingyun Li; Sayaka Masuko; Matt Suflita; Victor Schultz; Shawn D Nelson; Ujjwal Bhaskar; Jian Liu; Robert J Linhardt
Journal:  Org Lett       Date:  2014-04-04       Impact factor: 6.005
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.