| Literature DB >> 12743100 |
José M G Vilar1, Călin C Guet, Stanislas Leibler.
Abstract
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, which seems to capture many experimental aspects of the system.Entities:
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Year: 2003 PMID： 12743100 PMCID： PMC2172934 DOI： 10.1083/jcb.200301125
Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539