Literature DB >> 12743026

Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression.

Gerhard Christofori1.   

Abstract

Changes in cell-cell and cell-matrix adhesion accompany the transition from benign tumours to invasive, malignant cancer and the subsequent metastatic dissemination of tumour cells. This review discusses a possible role of cell adhesion molecules not only in redirecting a tumour cell's adhesive capabilities but also in modulating intracellular signalling, and with it, tumour malignancy.

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Year:  2003        PMID: 12743026      PMCID: PMC155986          DOI: 10.1093/emboj/cdg228

Source DB:  PubMed          Journal:  EMBO J        ISSN: 0261-4189            Impact factor:   11.598


  57 in total

Review 1.  The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.

Authors:  G Christofori; H Semb
Journal:  Trends Biochem Sci       Date:  1999-02       Impact factor: 13.807

2.  Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias.

Authors:  P Fogar; D Basso; C Pasquali; M De Paoli; C Sperti; G Roveroni; S Pedrazzoli; M Plebani
Journal:  Anticancer Res       Date:  1997 Mar-Apr       Impact factor: 2.480

3.  Tumor suppressor activity of neural cell adhesion molecule in colon carcinoma.

Authors:  J Roesler; E Srivatsan; F Moatamed; J Peters; E H Livingston
Journal:  Am J Surg       Date:  1997-09       Impact factor: 2.565

4.  Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.

Authors:  K Vleminckx; L Vakaet; M Mareel; W Fiers; F van Roy
Journal:  Cell       Date:  1991-07-12       Impact factor: 41.582

Review 5.  Morphogenetic roles of classic cadherins.

Authors:  M Takeichi
Journal:  Curr Opin Cell Biol       Date:  1995-10       Impact factor: 8.382

6.  Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs.

Authors:  J L Saffell; E J Williams; I J Mason; F S Walsh; P Doherty
Journal:  Neuron       Date:  1997-02       Impact factor: 17.173

Review 7.  CAM-FGF receptor interactions: a model for axonal growth.

Authors:  P Doherty; F S Walsh
Journal:  Mol Cell Neurosci       Date:  1996       Impact factor: 4.314

Review 8.  Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.

Authors:  W Birchmeier; J Behrens
Journal:  Biochim Biophys Acta       Date:  1994-05-27

9.  Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.

Authors:  S Islam; T E Carey; G T Wolf; M J Wheelock; K R Johnson
Journal:  J Cell Biol       Date:  1996-12       Impact factor: 10.539

10.  p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system.

Authors:  M Hamaguchi; N Matsuyoshi; Y Ohnishi; B Gotoh; M Takeichi; Y Nagai
Journal:  EMBO J       Date:  1993-01       Impact factor: 11.598

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  80 in total

Review 1.  Structure-based models of cadherin-mediated cell adhesion: the evolution continues.

Authors:  A W Koch; K L Manzur; W Shan
Journal:  Cell Mol Life Sci       Date:  2004-08       Impact factor: 9.261

Review 2.  Convergence of Wnt, beta-catenin, and cadherin pathways.

Authors:  W James Nelson; Roel Nusse
Journal:  Science       Date:  2004-03-05       Impact factor: 47.728

Review 3.  Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton.

Authors:  Marita Goodwin; Alpha S Yap
Journal:  J Mol Histol       Date:  2004-11       Impact factor: 2.611

4.  Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway.

Authors:  Jianfei Qi; Ning Chen; Junfu Wang; Chi-Hung Siu
Journal:  Mol Biol Cell       Date:  2005-06-29       Impact factor: 4.138

5.  Identification of a Hoxc8-regulated transcriptional network in mouse embryo fibroblast cells.

Authors:  Haiyan Lei; Aster H Juan; Moo-Sang Kim; Frank H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-22       Impact factor: 11.205

6.  Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma.

Authors:  D J Papachristou; V Gkretsi; Y Tu; X Shi; K Chen; H Larjava; U N M Rao; C Wu
Journal:  Histopathology       Date:  2007-08-17       Impact factor: 5.087

7.  p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion.

Authors:  Margaret D George; Robert N Wine; Brad Lackford; Grace E Kissling; Steven K Akiyama; Kenneth Olden; John D Roberts
Journal:  Biochem Cell Biol       Date:  2013-06-24       Impact factor: 3.626

8.  Single cell adhesion measuring apparatus (SCAMA): application to cancer cell lines of different metastatic potential and voltage-gated Na+ channel expression.

Authors:  Christopher P Palmer; Maria E Mycielska; Hakan Burcu; Kareem Osman; Timothy Collins; Rachel Beckerman; Rebecca Perrett; Helen Johnson; Ebru Aydar; Mustafa B A Djamgoz
Journal:  Eur Biophys J       Date:  2007-09-19       Impact factor: 1.733

9.  Fasciclin 2, the Drosophila orthologue of neural cell-adhesion molecule, inhibits EGF receptor signalling.

Authors:  Yanlan Mao; Matthew Freeman
Journal:  Development       Date:  2009-02       Impact factor: 6.868

Review 10.  Role of subtilisin-like convertases in cadherin processing or the conundrum to stall cadherin function by convertase inhibitors in cancer therapy.

Authors:  E J Müller; R Caldelari; H Posthaus
Journal:  J Mol Histol       Date:  2004-03       Impact factor: 2.611

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