Literature DB >> 12737516

Function and regulation of Aurora/Ipl1p kinase family in cell division.

Yu Wen Ke1, Zhen Dou, Jie Zhang, Xue Biao Yao.   

Abstract

During mitosis, the parent cell distributes its genetic materials equally into two daughter cells through chromosome segregation, a complex movements orchestrated by mitotic kinases and its effector proteins. Faithful chromosome segregation and cytokinesis ensure that each daughter cell receives a full copy of genetic materials of parent cell. Defects in these processes can lead to aneuploidy or polyploidy. Aurora/Ipl1p family, a class of conserved serine/threonine kinases, plays key roles in chromosome segregation and cytokinesis. This article highlights the function and regulation of Aurora/Ipl1p family in mitosis and provides potential links between aberrant regulation of Aurora/Ipl1p kinases and pathogenesis of human cancer.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12737516     DOI： 10.1038/sj.cr.7290152

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  24 in total

Review 1.  Chromosomal passengers: the four-dimensional regulation of mitotic events.

Authors:  Paola Vagnarelli; William C Earnshaw
Journal:  Chromosoma       Date:  2004-09-04       Impact factor: 4.316

2.  Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore.

Authors:  Yong Yang; Fang Wu; Tarsha Ward; Feng Yan; Quan Wu; Zhaoyang Wang; Tanisha McGlothen; Wei Peng; Tianpa You; Mingkuan Sun; Taixing Cui; Renming Hu; Zhen Dou; Jingde Zhu; Wei Xie; Zihe Rao; Xia Ding; Xuebiao Yao
Journal:  J Biol Chem       Date:  2008-07-17       Impact factor: 5.157

3.  Association of an aurora kinase a (AURKA) gene polymorphism with progression-free survival in patients with advanced urothelial carcinoma treated with the selective aurora kinase a inhibitor alisertib.

Authors:  Andrea Necchi; Giulia Pintarelli; Daniele Raggi; Patrizia Giannatempo; Francesca Colombo
Journal:  Invest New Drugs       Date:  2017-02-03       Impact factor: 3.850

4.  A G-quadruplex stabilizer induces M-phase cell cycle arrest.

Authors:  Yuan-Chin Tsai; Haiyan Qi; Chao-Po Lin; Ren-Kuo Lin; John E Kerrigan; Suzanne G Rzuczek; Edmond J LaVoie; Joseph E Rice; Daniel S Pilch; Yi Lisa Lyu; Leroy F Liu
Journal:  J Biol Chem       Date:  2009-06-16       Impact factor: 5.157

5.  SUV39H1 orchestrates temporal dynamics of centromeric methylation essential for faithful chromosome segregation in mitosis.

Authors:  Lingluo Chu; Tongge Zhu; Xing Liu; Ruoying Yu; Methode Bacanamwo; Zhen Dou; Youjun Chu; Hanfa Zou; Gary H Gibbons; Dongmei Wang; Xia Ding; Xuebiao Yao
Journal:  J Mol Cell Biol       Date:  2012-07-25       Impact factor: 6.216

6.  Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction.

Authors:  Peng Xia; Jinhua Zhou; Xiaoyu Song; Bing Wu; Xing Liu; Di Li; Shuyuan Zhang; Zhikai Wang; Huijuan Yu; Tarsha Ward; Jiancun Zhang; Yinmei Li; Xiaoning Wang; Yong Chen; Zhen Guo; Xuebiao Yao
Journal:  J Mol Cell Biol       Date:  2014-05-20       Impact factor: 6.216

Review 7.  Emerging roles for centromeres in meiosis I chromosome segregation.

Authors:  Gloria A Brar; Angelika Amon
Journal:  Nat Rev Genet       Date:  2008-12       Impact factor: 53.242

8.  The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability.

Authors:  J Du; X Cai; J Yao; X Ding; Q Wu; S Pei; K Jiang; Y Zhang; W Wang; Y Shi; Y Lai; J Shen; M Teng; H Huang; Q Fei; E S Reddy; J Zhu; C Jin; X Yao
Journal:  Oncogene       Date:  2008-02-25       Impact factor: 9.867

9.  Preclinical testing of selective Aurora kinase inhibitors on a medullary thyroid carcinoma-derived cell line.

Authors:  Chiara Tuccilli; Enke Baldini; Natalie Prinzi; Stefania Morrone; Salvatore Sorrenti; Angelo Filippini; Antonio Catania; Stefania Alessandrini; Roberta Rendina; Carmela Coccaro; Massimino D'Armiento; Salvatore Ulisse
Journal:  Endocrine       Date:  2015-07-28       Impact factor: 3.633

10.  A complex cell division machinery was present in the last common ancestor of eukaryotes.

Authors:  Laura Eme; David Moreira; Emmanuel Talla; Céline Brochier-Armanet
Journal:  PLoS One       Date:  2009-04-07       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.