Literature DB >> 12736451

Synthesis, conformational analysis and free radical scavenging activity of some new spiropyranoquinolinones.

Vassiliki Panteleon1, Panagiotis Marakos, Nicole Pouli, Emmanuel Mikros, Ioanna Andreadou.   

Abstract

A series of novel spiroadamantyl- and spirocyclical substituted pyranoquinolin-2-ones were synthesized and the conformation of the pyran ring was investigated. The free radical scavenging activity of the synthesized compounds was determined by their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH). All compounds tested scavenged the DPPH radical and among them derivatives possessing extended conjugation showed the highest activity.

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Year:  2003        PMID: 12736451     DOI: 10.1248/cpb.51.522

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Efficient synthesis and free-radical scavenging capacity of new 2,4-substituted tetrahydroquinolines prepared via BiCl₃-catalyzed three-component Povarov reaction, using N-vinylamides.

Authors:  Vladimir V Kouznetsov; Carlos M Meléndez Gómez; Luz K Luna Parada; John H Bermudez; Leonor Y Vargas Méndez; Amner Muñoz Acevedo
Journal:  Mol Divers       Date:  2011-09-25       Impact factor: 2.943

  1 in total

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