Literature DB >> 1273587

Thrombosis in association with atherosclerosis induced by dietary perturbations in dogs.

R Mahley, A W Nelson, V J Ferrans, D L Fry.   

Abstract

The distribution, severity, and complications of diet-induced atherosclerosis in dogs can be altered by changing the source of fat in the diet. Thrombosis and thromboembolic disease associated with atherosclerosis occurred with diets containing beef tallow and lard of coconut oil but were absent in dogs fed cottonseed oil as a source of fat. Experiemtnal animals with and without thrombosis are of value as models in elucidating the role of platelets and thrombostatic mechanisms in atherosclerosis.

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Year:  1976        PMID: 1273587     DOI: 10.1126/science.1273587

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

1.  The role of dietary fat and cholesterol in atherosclerosis and lipoprotein metabolism.

Authors:  R W Mahley
Journal:  West J Med       Date:  1981-01

2.  Cottonseed Oil Alleviates Ischemic Stroke-Induced Oxidative Stress Injury Via Activating the Nrf2 Signaling Pathway.

Authors:  Min Liu; Hao Li; Lixia Zhang; Yulong Ma; Weidong Mi; Zhipeng Xu; Yuxiang Song; Xiaoyan Wang; Ruitong Chu; Yunming Xiao; Miao Sun
Journal:  Mol Neurobiol       Date:  2021-01-14       Impact factor: 5.590

Review 3.  Dog models of human atherosclerotic cardiovascular diseases.

Authors:  Hui Zhao; Enqi Liu; Yong Q Zhang
Journal:  Mamm Genome       Date:  2022-10-15       Impact factor: 3.224

4.  Effects of diets high in saturated fat and cholesterol on the lipid composition of canine platelets.

Authors:  R E Pitas; G J Nelson; R M Jaffe; R W Mahley
Journal:  Lipids       Date:  1979-05       Impact factor: 1.880

5.  Canine hyperlipoproteinemia and atherosclerosis. Accumulation of lipid by aortic medial cells in vivo and in vitro.

Authors:  R W Mahley; T L Innerarity; K H Weisgraber; D L Fry
Journal:  Am J Pathol       Date:  1977-04       Impact factor: 4.307

6.  Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte.

Authors:  Min Liu; Zhipeng Xu; Long Wang; Lixia Zhang; Yi Liu; Jiangbei Cao; Qiang Fu; Yanhong Liu; Hao Li; Jingsheng Lou; Wugang Hou; Weidong Mi; Yulong Ma
Journal:  J Neuroinflammation       Date:  2020-09-11       Impact factor: 8.322

  6 in total

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