Literature DB >> 12735680

Synthesis and evaluation of cytotoxicity of stilbene analogues.

Sang Kook Lee1, Kyung Ae Nam, Yeon Hoi Hoe, Hye-Young Min, Eun-Young Kim, Hyojin Ko, Soyoung Song, Taeho Lee, Sanghee Kim.   

Abstract

Resveratrol analogs were newly synthesized and evaluated for cytotoxicity in cultured human lung and colon cancer cells. 3,5,4-Trimethoxy-trans-stilbene and 3,5,2',4'-tetramethoxy-trans-stilbene were found to be more potent rather than resveratrol. 3,4,5-Trimethoxy-4'-bromo-cis-stilbene was the most active among the test compounds.

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Year:  2003        PMID： 12735680     DOI： 10.1007/bf02976951

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  8 in total

1.  3,4',5-trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.

Authors:  Fahad S Aldawsari; Carlos A Velázquez-Martínez
Journal:  Invest New Drugs       Date:  2015-02-28       Impact factor: 3.850

2.  Metabolic engineering for resveratrol derivative biosynthesis in Escherichia coli.

Authors:  Yu Jeong Jeong; Su Gyeong Woo; Chul Han An; Hyung Jae Jeong; Young-Soo Hong; Young-Min Kim; Young Bae Ryu; Mun-Chual Rho; Woo Song Lee; Cha Young Kim
Journal:  Mol Cells       Date:  2015-02-25       Impact factor: 5.034

3.  3'-hydroxy-3,4,5,4'-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model.

Authors:  Hanna Piotrowska-Kempisty; Marcin Ruciński; Sylwia Borys; Małgorzata Kucińska; Mariusz Kaczmarek; Piotr Zawierucha; Marcin Wierzchowski; Dawid Łażewski; Marek Murias; Jadwiga Jodynis-Liebert
Journal:  Sci Rep       Date:  2016-09-02       Impact factor: 4.379

4.  Engineering yeast for high-level production of stilbenoid antioxidants.

Authors:  Mingji Li; Konstantin Schneider; Mette Kristensen; Irina Borodina; Jens Nielsen
Journal:  Sci Rep       Date:  2016-11-11       Impact factor: 4.379

5.  Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis.

Authors:  Pravat Kumar Parida; Barun Mahata; Abhisek Santra; Sohini Chakraborty; Zhumur Ghosh; Sanghamitra Raha; Anup Kumar Misra; Kaushik Biswas; Kuladip Jana
Journal:  Cell Death Dis       Date:  2018-05-01       Impact factor: 8.469

6.  Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases.

Authors:  Aleksandra K Greer; Nikhil R Madadi; Stacie M Bratton; Sarah D Eddy; Zofia Mazerska; Howard P Hendrickson; Peter A Crooks; Anna Radominska-Pandya
Journal:  Chem Res Toxicol       Date:  2014-03-11       Impact factor: 3.739

Review 7.  In Vitro and In Vivo Effects of Flavonoids on Peripheral Neuropathic Pain.

Authors:  Paramita Basu; Arpita Basu
Journal:  Molecules       Date:  2020-03-05       Impact factor: 4.411

8.  Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.

Authors:  Hao Zhang; Yanan Chen; Yueping Chen; Shuli Ji; Peilu Jia; Yue Li; Tian Wang
Journal:  J Anim Sci Biotechnol       Date:  2020-06-01
  8 in total

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