The high zero-flow pressure phenomenon in coronary circulation: a simulation study.

A dynamic simulation was performed in order to study the high zero-flow pressure phenomenon by using an electronic model of the coronary vessel. The objective of this study was to establish a relationship between the diastolic arterial pressure and diastolic arterial flow. The simulated study showed that this relationship is approximately linear with a zero flow pressure intercept of approximately 40 mmHg. This result is consistent with the results obtained in animal experimentation conducted by others.