Literature DB >> 12735287

[Hepatic splenosis diagnosed by fine-needle cytology].

P Galloro1, G Marino Marsilia, O Nappi.   

Abstract

A case of hepatic splenosis, diagnosed by FNA cytology, in a 56 years old cirrhotic man is reported. The cytologic material, aspirated from a 4.8 cm "suspicious for hepatocarcinoma" nodule, showed, within a hematic background, small-medium sized lymphoid cells, neutrophils and eosinophils granulocytes, histiocytes with large cytoplasm, plasma cells; mixtures of these cells, within a reticular network, were often aggregated in large structures, in which endothelial cells organized in vascular-like structures were also visible. The cell block, showed sinusoidal structures, lymphoid follicular aggregates and fibrous septa, strongly suggesting the micromorphology of the normal spleen. Splenosis is an autotransplant of splenic tissue, morphologically organized in non-capsulated, functioning, self-limited nodules, secondary to a post-traumatic splenectomy. Usual presentation of this condition is the presence of several bluish nodules on the peritoneal surface. Nevertheless, sporadic cases in other organs have been reported. To the best of our review of the Medical Literature, a hepatic splenosis is an exceptional even and the present is the first case in this location diagnosed by FNA cytology. The present one is also the case with the largest latency between the splenectomy and the splenosis detection (43 years).

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Mesh:

Year:  2003        PMID: 12735287

Source DB:  PubMed          Journal:  Pathologica        ISSN: 0031-2983


  3 in total

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Authors:  Tara A Saunders; Theodore R Miller; Elham Khanafshar
Journal:  J Gastrointest Oncol       Date:  2016-04

2.  Solitary perihepatic splenosis mimicking liver lesion: a case report and literature review.

Authors:  Chao Wu; Binhao Zhang; Lin Chen; Bixiang Zhang; Xiaoping Chen
Journal:  Medicine (Baltimore)       Date:  2015-03       Impact factor: 1.889

3.  Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy.

Authors:  M Abu Hilal; A Harb; B Zeidan; B Steadman; J N Primrose; N W Pearce
Journal:  World J Surg Oncol       Date:  2009-01-05       Impact factor: 2.754

  3 in total

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