Literature DB >> 12734745

Bioavailability of a pediatric amlodipine suspension.

Dorothy A Lyszkiewicz1, Zina Levichek, Eran Kozer, Yaron Yagev, Myla Moretti, Marjie Hard, Gideon Koren.   

Abstract

Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in 20 healthy adult volunteers. Bioequivalence of the suspension was not different from the tablets. These results support the use of the suspension in children who cannot take the tablet.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12734745     DOI： 10.1007/s00467-003-1088-2

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN： 0931-041X            Impact factor:   3.714


  12 in total

Review 1.  United States Food and Drug Administration requirements for approval of generic drug products.

Authors:  M C Meyer
Journal:  J Clin Psychiatry       Date:  2001       Impact factor: 4.384

2.  Absorption of amlodipine unaffected by food. Solid dose equivalent to solution dose.

Authors:  J K Faulkner; M L Hayden; L F Chasseaud; T Taylor
Journal:  Arzneimittelforschung       Date:  1989-07

3.  Antihypertensive efficacy of amlodipine in children with chronic kidney diseases.

Authors:  R O von Vigier; L M Franscini; N D Bianda; R Pfister; C Casaulta Aebischer; M G Bianchetti
Journal:  J Hum Hypertens       Date:  2001-06       Impact factor: 3.012

4.  Efficacy of amlodipine in pediatric patients with hypertension.

Authors:  K B Tallian; M C Nahata; M A Turman; J D Mahan; J R Hayes; M I Mentser
Journal:  Pediatr Nephrol       Date:  1999-05       Impact factor: 3.714

5.  Dicloxacillin absorption and elimination in children.

Authors:  A L Smith; C A Meeks; J R Koup; K E Opheim; A Weber; C T Vishwanathan
Journal:  Dev Pharmacol Ther       Date:  1990

6.  Pharmacokinetic assessment of an oral enalapril suspension for use in children.

Authors:  R K Rippley; J Connor; J Boyle; T E Bradstreet; E Hand; M W Lo; M G Murphy
Journal:  Biopharm Drug Dispos       Date:  2000-12       Impact factor: 1.627

7.  Use of calcium-channel blockers in pediatric renal transplant recipients.

Authors:  D M Silverstein; J Palmer; H J Baluarte; C Brass; S B Conley; M S Polinsky
Journal:  Pediatr Transplant       Date:  1999-11

8.  A randomized prospective crossover trial of amlodipine in pediatric hypertension.

Authors:  J W Rogan; D A Lyszkiewicz; D Blowey; S Khattak; G S Arbus; G Koren
Journal:  Pediatr Nephrol       Date:  2000-10       Impact factor: 3.714

9.  Treatment of hypertensive children with amlodipine.

Authors:  J T Flynn; W E Smoyer; T E Bunchman
Journal:  Am J Hypertens       Date:  2000-10       Impact factor: 2.689

10.  Amlodipine once-daily in systemic hypertension.

Authors:  J P Pfammatter; C Clericetti-Affolter; A C Truttmann; K Busch; R Laux-End; M G Bianchetti
Journal:  Eur J Pediatr       Date:  1998-08       Impact factor: 3.183
View more
  5 in total

Review 1.  Formulations for children: problems and solutions.

Authors:  Hannah K Batchelor; John F Marriott
Journal:  Br J Clin Pharmacol       Date:  2015-03       Impact factor: 4.335

2.  Superior palatability of crushed lercanidipine compared with amlodipine among children.

Authors:  Gregorio Milani; Monica Ragazzi; Giacomo D Simonetti; Gian P Ramelli; Mattia Rizzi; Mario G Bianchetti; Emilio F Fossali
Journal:  Br J Clin Pharmacol       Date:  2010-02       Impact factor: 4.335

3.  Bioequivalence of dispersed stavudine: opened versus closed capsule dosing.

Authors:  Steve Innes; Jennifer Norman; Pete Smith; Marlize Smuts; Edmund Capparelli; Bernd Rosenkranz; Mark Cotton
Journal:  Antivir Ther       Date:  2011

4.  Extemporaneous Compounding and Physiological Modeling of Amlodipine/Valsartan Suspension.

Authors:  Wafa' J Aabed; Asma H Radwan; Abdel Naser Zaid; Naser Y Shraim
Journal:  Int J Hypertens       Date:  2021-03-12       Impact factor: 2.420

Review 5.  Formulations of Amlodipine: A Review.

Authors:  Muhammad Ali Sheraz; Syed Furqan Ahsan; Marium Fatima Khan; Sofia Ahmed; Iqbal Ahmad
Journal:  J Pharm (Cairo)       Date:  2016-10-16
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.