Literature DB >> 12733966

Application of a new method of nonlinear dynamical system identification to biochemical problems.

A V Karnaukhov1, E V Karnaukhova.   

Abstract

The system identification method for a variety of nonlinear dynamic models is elaborated. The problem of identification of an original nonlinear model presented as a system of ordinary differential equations in the Cauchy explicit form with a polynomial right part reduces to the solution of the system of linear equations for the constants of the dynamical model. In other words, to construct an integral model of the complex system (phenomenon), it is enough to collect some data array characterizing the time-course of dynamical parameters of the system. Collection of such a data array has always been a problem. However difficulties emerging are, as a rule, not principal and may be overcome almost without exception. The potentialities of the method under discussion are demonstrated by the example of the test problem of multiparametric nonlinear oscillator identification. The identification method proposed may be applied to the study of different biological systems and in particular the enzyme kinetics of complex biochemical reactions.

Mesh:

Substances:

Year:  2003        PMID: 12733966     DOI: 10.1023/a:1023001614596

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN: 0006-2979            Impact factor:   2.487


  3 in total

1.  Numerical Matrices Method for nonlinear system identification and description of dynamics of biochemical reaction networks.

Authors:  Alexey V Karnaukhov; Elena V Karnaukhova; James R Williamson
Journal:  Biophys J       Date:  2007-03-09       Impact factor: 4.033

2.  Priming nonlinear searches for pathway identification.

Authors:  Siren R Veflingstad; Jonas Almeida; Eberhard O Voit
Journal:  Theor Biol Med Model       Date:  2004-09-14       Impact factor: 2.432

3.  Informational Theory of Aging: The Life Extension Method Based on the Bone Marrow Transplantation.

Authors:  Alexey V Karnaukhov; Elena V Karnaukhova; Larisa A Sergievich; Natalia A Karnaukhova; Elena V Bogdanenko; Irina A Manokhina; Valery N Karnaukhov
Journal:  J Biophys       Date:  2015-09-30
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.