| Literature DB >> 12733496 |
S G Izmaĭlov1, G A Izmaĭlov, I V Zaikonnikova, V S Reznik, V Iu Tereshchenko, S M Gorbunov, G V Evranova, R Sh Shaĭmardanov, A A Muslinkin, A A Bodrov, R A Abdulkhakov, V M Lazarev, M Iu Kedrin, E A Gurylev, L Kh Mavziutov, L Kh Mavziutov, K V Malyshev, R N Gabbasov, I Z Shafikov, O S Kochnev, I V Podushkina, A G Izmaĭlov, V N Garaev, I F Sharafislamov, M Kh Gerasimova.
Abstract
Results of clinical trial of the new pyrimidine derivative--ximedone are presented. The drug was administered per os 0.5 g x 4 times a day (0.5 h before meals). Total course dose achieved 60 g. Ximedone implementation for complex treatment of burns, trophic ulcer of lower limbs, different inflammations demonstrated positive results. Prophylaxy administration of the drug in abdominal surgery at acute appendix resulted with lower incidence of postoperative complications. High efficacy and good tolerability of the drug allows to recommend it for wide medical use.Entities:
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Year: 2002 PMID： 12733496
Source DB: PubMed Journal: Antibiot Khimioter ISSN： 0235-2990