Literature DB >> 12732316

Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation.

Marc Morant1, Søren Bak, Birger Lindberg Møller, Danièle Werck-Reichhart.   

Abstract

Cytochromes P450 catalyse extremely diverse and often complex regiospecific and/or stereospecific reactions in the biosynthesis or catabolism of plant bioactive molecules. Engineered P450 expression is needed for low-cost production of antineoplastic drugs such as taxol or indole alkaloids and offers the possibility to increase the content of nutraceuticals such as phytoestrogens and antioxidants in plants. Natural products may serve important functions in plant defence and metabolic engineering of P450s is a prime target to improve plant defence against insects and pathogens. Herbicides, pollutants and other xenobiotics are metabolised by some plant P450 enzymes. These P450s are tools to modify herbicide tolerance, as selectable markers and for bioremediation.

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Year:  2003        PMID： 12732316     DOI： 10.1016/s0958-1669(03)00024-7

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  69 in total

1.  Cytochromes p450.

Authors:  Søren Bak; Fred Beisson; Gerard Bishop; Björn Hamberger; René Höfer; Suzanne Paquette; Danièle Werck-Reichhart
Journal:  Arabidopsis Book       Date:  2011-10-06

Review 2.  Plant cytochrome P450s: nomenclature and involvement in natural product biosynthesis.

Authors:  Saiema Rasool; Rozi Mohamed
Journal:  Protoplasma       Date:  2015-09-12       Impact factor: 3.356

3.  Isolation and characterization of two hydroperoxide lyase genes from grape berries : HPL isogenes in Vitis vinifera grapes.

Authors:  Bao-Qing Zhu; Xiao-Qing Xu; Yu-Wen Wu; Chang-Qing Duan; Qiu-Hong Pan
Journal:  Mol Biol Rep       Date:  2012-02-09       Impact factor: 2.316

Review 4.  Tapetum: regulation and role in sporopollenin biosynthesis in Arabidopsis.

Authors:  Liang Liu; Xiu-duo Fan
Journal:  Plant Mol Biol       Date:  2013-06-12       Impact factor: 4.076

Review 5.  The outlook for protein engineering in crop improvement.

Authors:  A Gururaj Rao
Journal:  Plant Physiol       Date:  2008-05       Impact factor: 8.340

Review 6.  Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.

Authors:  F Peter Guengerich; Qian Cheng
Journal:  Pharmacol Rev       Date:  2011-07-07       Impact factor: 25.468

7.  The enzymatic basis for pesticide bioremediation.

Authors:  Colin Scott; Gunjan Pandey; Carol J Hartley; Colin J Jackson; Matthew J Cheesman; Matthew C Taylor; Rinku Pandey; Jeevan L Khurana; Mark Teese; Chris W Coppin; Kahli M Weir; Rakesh K Jain; Rup Lal; Robyn J Russell; John G Oakeshott
Journal:  Indian J Microbiol       Date:  2008-05-01       Impact factor: 2.461

Review 8.  Metabolism-based herbicide resistance and cross-resistance in crop weeds: a threat to herbicide sustainability and global crop production.

Authors:  Qin Yu; Stephen Powles
Journal:  Plant Physiol       Date:  2014-08-08       Impact factor: 8.340

9.  De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis.

Authors:  Chao Sun; Ying Li; Qiong Wu; Hongmei Luo; Yongzhen Sun; Jingyuan Song; Edmund M K Lui; Shilin Chen
Journal:  BMC Genomics       Date:  2010-04-24       Impact factor: 3.969

10.  CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen.

Authors:  Marc Morant; Kirsten Jørgensen; Hubert Schaller; Franck Pinot; Birger Lindberg Møller; Danièle Werck-Reichhart; Søren Bak
Journal:  Plant Cell       Date:  2007-05-11       Impact factor: 11.277
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