Literature DB >> 12732075

Potts ferromagnets on coexpressed gene networks: identifying maximally stable partitions.

Himanshu Agrawal1, Eytan Domany.   

Abstract

Clustering gene expression data by exploiting phase transitions in granular ferromagnets requires transforming the data to a granular substrate. We present a method using the recently introduced homogeneity order parameter Lambda [H. Agrawal, Phys. Rev. Lett. 89, 268702 (2002)]] for optimizing the parameter controlling the "granularity" and thus the stability of partitions. The model substrates obtained for gene expression data have a highly granular structure. We explore properties of phase transition in high q ferromagnetic Potts models on these substrates and show that the maximum of the width of superparamagnetic domain, corresponding to maximally stable partitions, coincides with the minimum of Lambda.

Mesh:

Year:  2003        PMID: 12732075     DOI: 10.1103/PhysRevLett.90.158102

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  6 in total

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  6 in total

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