Literature DB >> 12729777

Survival in patients under 45 years with squamous cell carcinoma of the oral tongue.

S Manuel1, S K N Raghavan, M Pandey, P Sebastian.   

Abstract

Squamous cell cancer among young adults is rare and thought to have aggressive biological behaviour and poor prognosis. Clinical case records of 76 patients under the age of 45 years treated for squamous cell carcinoma (SCC) of the oral tongue were retrospectively analysed to calculate the survival rates and the predictors of survival. The overall survival (OS) and disease free survival (DFS) at 5 year were 78.0% and 57.4% respectively. Tumour status, pathological node status, surgical clearance, the selection of appropriate treatment, type of primary and neck surgery, were found to significantly influence the survival rates. Young patients with SCC of the oral tongue were seen to have a comparable outcome and prognosis compared to that in older patients.

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Mesh：

Year:  2003        PMID： 12729777     DOI： 10.1054/ijom.2002.0271

Source DB:  PubMed          Journal:  Int J Oral Maxillofac Surg        ISSN： 0901-5027            Impact factor:   2.789


  14 in total

1.  Squamous cell carcinoma of the oral tongue in the pediatric age group: a matched-pair analysis of survival.

Authors:  Luc G T Morris; Snehal G Patel; Jatin P Shah; Ian Ganly
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2010-07

Review 2.  Tongue carcinoma in young adults: a review of the literature.

Authors:  A Paderno; R Morello; C Piazza
Journal:  Acta Otorhinolaryngol Ital       Date:  2018-06       Impact factor: 2.124

3.  HPV-16/18 detection does not affect the prognosis of head and neck squamous cell carcinoma in younger and older patients.

Authors:  Luciano Marques-Silva; Lucyana Conceição Farias; Carlos Alberto de Carvalho Fraga; Marcos Vinícius Macedo de Oliveira; Cláudio Marcelo Cardos; Thiago Fonseca-Silva; Carolina Cavalieri Gomes; Alfredo Maurício Batista De-Paula; Ricardo Santiago Gomez; André Luiz Sena Guimarães
Journal:  Oncol Lett       Date:  2012-02-01       Impact factor: 2.967

4.  The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults.

Authors:  Wojciech Gawecki; Magdalena Kostrzewska-Poczekaj; Marzena Gajecka; Piotr Milecki; Krzysztof Szyfter; Witold Szyfter
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-07-26       Impact factor: 2.503

Review 5.  Oral squamous cell cancer: early detection and the role of alcohol and smoking.

Authors:  Anna G Zygogianni; George Kyrgias; Petros Karakitsos; Amanta Psyrri; John Kouvaris; Nikolaos Kelekis; Vassilis Kouloulias
Journal:  Head Neck Oncol       Date:  2011-01-06

6.  Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients.

Authors:  Andreas Knopf; Justine Lempart; Murat Bas; Julia Slotta-Huspenina; Naglaa Mansour; Marie Kristin Fritsche
Journal:  Oncotarget       Date:  2015-02-20

7.  Cytogenetic significance of chromosome 17 aberrations and P53 gene mutations as prognostic markers in oral squamous cell carcinoma.

Authors:  Walid Zedan; Mohamed I Mourad; Sherin M Abd El-Aziz; Nagla M Salamaa; Asem A Shalaby
Journal:  Diagn Pathol       Date:  2015-02-22       Impact factor: 2.644

8.  A Comparison of Clinicopathological Differences in Oral Squamous Cell Carcinoma in Patients Below and Above 40 Years of Age.

Authors:  Supriya Nikita Kapila; Srikant Natarajan; Karen Boaz
Journal:  J Clin Diagn Res       Date:  2017-09-01

9.  Tongue squamous cell carcinoma as a possible distinct entity in patients under 40 years old.

Authors:  Qi-Gen Fang; Shuang Shi; Fa-Yu Liu; Chang-Fu Sun
Journal:  Oncol Lett       Date:  2014-04-09       Impact factor: 2.967

10.  Oral tongue cancer in public hospitals in Madrid, Spain (1990-2008).

Authors:  A-I García-Kass; A Herrero-Sánchez; G Esparza-Gómez
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-11-01
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