| Literature DB >> 12729630 |
Elizabeth A Jefferson1, Eric E Swayze, Stephen A Osgood, Alycia Miyaji, Lisa M Risen, Lawrence B Blyn.
Abstract
Novel quinolone-macrocycle conjugates displayed submicromolar antibacterial activity against Escherichia coli and Staphylococcus aureus bacterial strains. An analogous open-chain structure was not active at 100 microM against the same pathogenic strains.Entities:
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Year: 2003 PMID： 12729630 DOI： 10.1016/s0960-894x(03)00285-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823