Literature DB >> 12727624

Intrinsic T cell defects in systemic autoimmunity.

Philip L Kong1, Jared M Odegard, Farida Bouzahzah, Jin-Young Choi, Leah D Eardley, Christina E Zielinski, Joseph E Craft.   

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of T cell tolerance to nuclear antigens. Studies in mice and humans have demonstrated that T cells from individuals with lupus are abnormal. Here, we review the known T cell defects in lupus and their possible biochemical nature, genetic causes, and significance for lupus pathogenesis.

Entities:  

Mesh：

Year:  2003        PMID： 12727624     DOI： 10.1111/j.1749-6632.2003.tb06033.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  7 in total

1.  T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1.

Authors:  Weici Zhang; Yoko Ono; Yoshinori Miyamura; Christopher L Bowlus; M Eric Gershwin; Emanual Maverakis
Journal:  J Autoimmun       Date:  2011-06-01       Impact factor: 7.094

2.  Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.

Authors:  Carla M Cuda; Shiwu Li; Shujuan Liang; Yiming Yin; Hari Hara S K Potula; Zhiwei Xu; Mayami Sengupta; Yifang Chen; Edward Butfiloski; Henry Baker; Lung-Ji Chang; Igor Dozmorov; Eric S Sobel; Laurence Morel
Journal:  J Immunol       Date:  2011-12-16       Impact factor: 5.422

3.  Normalization of CD4+ T cell metabolism reverses lupus.

Authors:  Yiming Yin; Seung-Chul Choi; Zhiwei Xu; Daniel J Perry; Howard Seay; Byron P Croker; Eric S Sobel; Todd M Brusko; Laurence Morel
Journal:  Sci Transl Med       Date:  2015-02-11       Impact factor: 17.956

4.  Polymeric dexamethasone prodrugs attenuate lupus nephritis in MRL/lpr mice with reduced glucocorticoid toxicity.

Authors:  Zhifeng Zhao; Haochen Jiang; Xiaoke Xu; Zhenshan Jia; Rongguo Ren; Kirk W Foster; Xin Wei; Ningrong Chen; Steven R Goldring; Mary K Crow; Dong Wang
Journal:  Nanomedicine       Date:  2022-06-26       Impact factor: 6.096

5.  Lupus autoimmunity altered by cellular methylation metabolism.

Authors:  Mei-Ling Yang; Alaric J P Gee; Renelle J Gee; Cecilia I Zurita-Lopez; Shilpi Khare; Steven G Clarke; Mark J Mamula
Journal:  Autoimmunity       Date:  2012-11-01       Impact factor: 2.815

6.  Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells.

Authors:  Sandeep Krishnan; Yuang-Taung Juang; Bhabadeb Chowdhury; Abigail Magilavy; Carolyn U Fisher; Hang Nguyen; Madhusoodana P Nambiar; Vasileios Kyttaris; Arthur Weinstein; Rena Bahjat; Polly Pine; Violeta Rus; George C Tsokos
Journal:  J Immunol       Date:  2008-12-01       Impact factor: 5.422

7.  Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity.

Authors:  Jessica C Fanzo; Wen Yang; So Young Jang; Sanjay Gupta; Qinzhong Chen; Ayesha Siddiq; Steven Greenberg; Alessandra B Pernis
Journal:  J Clin Invest       Date:  2006-02-09       Impact factor: 14.808
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.