| Literature DB >> 12727400 |
D J Stickler1, G L Jones, A D Russell.
Abstract
Urinary catheters often become encrusted and blocked by crystalline Proteus mirabilis biofilms. Results of experiments in a laboratory model of a Foley catheterised bladder infected with P mirabilis showed that when retention balloons were inflated with a solution of triclosan (10 g/L), the catheters drained freely for at least 7 days. Triclosan became impregnated throughout the silicone catheter material and completely inhibited the formation of crystalline biofilm, whereas catheters inflated with water became blocked in 24 h. Our observations suggest a way to control a common complication in patients with long-term indwelling bladder catheters.Entities:
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Year: 2003 PMID: 12727400 DOI: 10.1016/s0140-6736(03)13104-2
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321