Literature DB >> 12726855

Cdk2 dethroned as master of S phase entry.

Philip W Hinds1.   

Abstract

The prevailing view of cdk2 as a critical regulator of cell cycle progression and optimal therapeutic target in cancer cells is now challenged by the observation that tumor cells deficient in cdk2 protein and kinase activity are not impaired in proliferation.

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Year:  2003        PMID： 12726855     DOI： 10.1016/s1535-6108(03)00084-9

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

1.  Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia.

Authors:  Lan Wang; Guang-Biao Zhou; Ping Liu; Jun-Hong Song; Yang Liang; Xiao-Jing Yan; Fang Xu; Bing-Shun Wang; Jian-Hua Mao; Zhi-Xiang Shen; Sai-Juan Chen; Zhu Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-14       Impact factor: 11.205

2.  Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells.

Authors:  Nupoor Prasad; Akash Sabarwal; Umesh C S Yadav; Rana P Singh
Journal:  J Biosci       Date:  2018-06       Impact factor: 1.826

3.  Pan-Cancer and Single-Cell Analysis Reveals CENPL as a Cancer Prognosis and Immune Infiltration-Related Biomarker.

Authors:  Ziyang Feng; Yu Chen; Changjing Cai; Jun Tan; Ping Liu; Yihong Chen; Hong Shen; Shan Zeng; Ying Han
Journal:  Front Immunol       Date:  2022-06-30       Impact factor: 8.786

4.  S-Like-Phase Cyclin-Dependent Kinases Stabilize the Epstein-Barr Virus BDLF4 Protein To Temporally Control Late Gene Transcription.

Authors:  Yoshitaka Sato; Takahiro Watanabe; Chihiro Suzuki; Yuichi Abe; H M Abdullah Al Masud; Tomoki Inagaki; Masahiro Yoshida; Takeshi Suzuki; Fumi Goshima; Jun Adachi; Takeshi Tomonaga; Takayuki Murata; Hiroshi Kimura
Journal:  J Virol       Date:  2019-04-03       Impact factor: 5.103

5.  Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

Authors:  Anders Ström; Johan Hartman; James S Foster; Silke Kietz; Jay Wimalasena; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-26       Impact factor: 11.205

6.  Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development.

Authors:  Kyoko Kitagawa; Kiyoshi Shibata; Akinobu Matsumoto; Masaki Matsumoto; Tatsuya Ohhata; Keiichi I Nakayama; Hiroyuki Niida; Masatoshi Kitagawa
Journal:  Mol Cell Biol       Date:  2014-07       Impact factor: 4.272

7.  Molecular docking of 1H-pyrazole derivatives to receptor tyrosine kinase and protein kinase for screening potential inhibitors.

Authors:  Vishalakshi Gopalapura Javaregowda; Beeranahally Haruvegowda Doreswamy; Srikantamurthy Ningaiah; Umesha K Bhadraiah; Kempaiah Kemparaju; Mahendra Madegowda
Journal:  Bioinformation       Date:  2014-07-22

8.  A novel CDK-2 homolog identified in lamprey, Lampetra japonica, with roles in apoptosis.

Authors:  Yang Xu; Yang Tian; Huan Zhao; Nan Zheng; Kaixia Ren; Qingwei Li
Journal:  Fish Physiol Biochem       Date:  2019-07-19       Impact factor: 2.794

9.  Cyclin-dependent kinase 2 protects podocytes from apoptosis.

Authors:  Pauliina Saurus; Sara Kuusela; Vincent Dumont; Eero Lehtonen; Christopher L Fogarty; Mariann I Lassenius; Carol Forsblom; Markku Lehto; Moin A Saleem; Per-Henrik Groop; Sanna Lehtonen
Journal:  Sci Rep       Date:  2016-02-15       Impact factor: 4.379

10.  Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death.

Authors:  Pavel Spirin; Elena Shyrokova; Timofey Lebedev; Elmira Vagapova; Polina Smirnova; Alexey Kantemirov; Sergey A Dyshlovoy; Gunhild von Amsberg; Maxim Zhidkov; Vladimir Prassolov
Journal:  Mar Drugs       Date:  2021-08-27       Impact factor: 5.118
  10 in total

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