| Literature DB >> 12725574 |
U K Mazumder1, M Gupta, L Manikandan, S Bhattacharya, P K Haldar, S Roy.
Abstract
The methanol extract of the whole plant of Vernonia cinerea Less. was evaluated for its anti-inflammatory activity in acute (carrageenin, histamine and serotonin induced rat paw edema) and a chronic model (cotton pouch induced granuloma). The methanol extract (250 and 500 mg/kg(-1) p.o.) exhibited significant activity (p < 0.001) against all phlogistic agents used in a dose dependant manner. In the chronic model (cotton pouch granuloma method) the methanol extract exhibited significant anti-inflammatory activity. All these effects were compared with standard drug phenylbutazone (100 mg/kg(-1) p.o.).Entities:
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Year: 2003 PMID： 12725574 DOI： 10.1078/094471103321659915
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340