Literature DB >> 12724300

R/qtl: QTL mapping in experimental crosses.

Karl W Broman1, Hao Wu, Saunak Sen, Gary A Churchill.   

Abstract

SUMMARY: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates. AVAILABILITY: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.

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Year:  2003        PMID: 12724300     DOI: 10.1093/bioinformatics/btg112

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  1439 in total

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4.  Genetic mapping of adaptation reveals fitness tradeoffs in Arabidopsis thaliana.

Authors:  Jon Ågrena; Christopher G Oakley; John K McKay; John T Lovell; Douglas W Schemske
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-09       Impact factor: 11.205

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6.  Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome.

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10.  Linking cellular zinc status to body weight and fat mass: mapping quantitative trait loci in Znt7 knockout mice.

Authors:  Surapun Tepaamorndech; Catherine P Kirschke; Liping Huang
Journal:  Mamm Genome       Date:  2014-04-26       Impact factor: 2.957

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