BACKGROUND: Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence. AIMS: To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment. METHOD: A community sample of 1045 dementia-free individuals aged 75 years and over was examined by neuropsychological testing in a three-wave longitudinal study. RESULTS: Prevalence rates ranged from 3% to 20%, depending on the concept applied. The annual incidence rates applying different case definitions varied from 8 to 77 per 1000 person-years. Rates of conversion to dementia over 2.6 years ranged from 23% to 47%. CONCLUSIONS: Mild cognitive impairment is frequent in older people. Prevalence, incidence and predictive validities are highly dependent on the diagnostic criteria applied.
BACKGROUND: Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence. AIMS: To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment. METHOD: A community sample of 1045 dementia-free individuals aged 75 years and over was examined by neuropsychological testing in a three-wave longitudinal study. RESULTS: Prevalence rates ranged from 3% to 20%, depending on the concept applied. The annual incidence rates applying different case definitions varied from 8 to 77 per 1000 person-years. Rates of conversion to dementia over 2.6 years ranged from 23% to 47%. CONCLUSIONS: Mild cognitive impairment is frequent in older people. Prevalence, incidence and predictive validities are highly dependent on the diagnostic criteria applied.
Authors: Ranjan Duara; David A Loewenstein; Maria T Greig; Elizabeth Potter; Warren Barker; Ashok Raj; John Schinka; Amy Borenstein; Michael Schoenberg; Yougui Wu; Jessica Banko; Huntington Potter Journal: Am J Geriatr Psychiatry Date: 2011-11 Impact factor: 4.105
Authors: R O Roberts; Y E Geda; D S Knopman; R H Cha; V S Pankratz; B F Boeve; E G Tangalos; R J Ivnik; W A Rocca; R C Petersen Journal: Neurology Date: 2012-01-25 Impact factor: 9.910
Authors: Sujuan Gao; Frederick W Unverzagt; Kathleen S Hall; Kathleen A Lane; Jill R Murrell; Ann M Hake; Valerie Smith-Gamble; Hugh C Hendrie Journal: Am J Geriatr Psychiatry Date: 2013-07-03 Impact factor: 4.105
Authors: Emily H Trittschuh; Paul K Crane; Eric B Larson; Brenna Cholerton; Wayne C McCormick; Susan M McCurry; James D Bowen; Laura D Baker; Suzanne Craft Journal: J Alzheimers Dis Date: 2011 Impact factor: 4.472
Authors: Sarah E Cook; Michael Marsiske; Kelsey R Thomas; Frederick W Unverzagt; Virginia G Wadley; Jessica B S Langbaum; Michael Crowe Journal: J Int Neuropsychol Soc Date: 2012-10-25 Impact factor: 2.892